C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: integrin, alpha 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000077943 ITGA8 9606 - 10:15513949-15720125 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000378076 ITGA8-001 15513949-15720125 protein_coding
  ENST00000468882 ITGA8-003 15611510-15644145 processed_transcript
  ENST00000477064 ITGA8-002 15596513-15604270 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000378076
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000378076 1.630±0.00 21.553±0.00 1.525±0.00 0.768±0.38 0.691±0.08 1.502±0.65 1.467±0.58 2.065±1.84 0.122±0.00 10.151±2.48 0.980±0.47 1.803±0.70 0.070±0.07 3.563±3.26

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00088I CIL_00088I_0001 VISTA 10:15191068-15798325
CIL_0002HM CIL_0002HM_0001 CGP 10:15513949-15860520

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001656 IEA metanephros development
GO:0001822 IMP kidney development
GO:0005783 IDA endoplasmic reticulum
GO:0005886 TAS plasma membrane
GO:0005925 IDA focal adhesion
GO:0007160 IMP cell-matrix adhesion
GO:0007229 IEA integrin-mediated signaling pathway
GO:0007420 IEA brain development
GO:0007613 IEA memory
GO:0008305 TAS integrin complex
GO:0009986 IDA cell surface
GO:0014069 IEA postsynaptic density
GO:0016337 NAS single organismal cell-cell adhesion
GO:0030030 IEA cell projection organization
GO:0030198 TAS extracellular matrix organization
GO:0030511 IEA positive regulation of transforming growth factor beta receptor signaling pathway
GO:0032591 IEA dendritic spine membrane
GO:0034446 IMP substrate adhesion-dependent cell spreading
GO:0034678 TAS integrin alpha8-beta1 complex
GO:0042472 IEA inner ear morphogenesis
GO:0043204 IEA perikaryon
GO:0045177 IEA apical part of cell
GO:0045184 IEA establishment of protein localization
GO:0046872 IEA metal ion binding
GO:0048333 IEP mesodermal cell differentiation
GO:0048745 IEA smooth muscle tissue development
GO:2000721 IEA positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078717 itga8 integrin, alpha 8 protein_coding Danio_rerio
ENSMUSG00000026768 Itga8 integrin alpha 8 protein_coding Mus_musculus

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