C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: integrin alpha 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026768 Itga8 10090 - 2:12106632-12301920 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000028106 Itga8-001 12106632-12301920 protein_coding
  ENSMUST00000129370 Itga8-004 12182661-12193312 retained_intron
  ENSMUST00000130548 Itga8-003 12286964-12301588 processed_transcript
  ENSMUST00000141477 Itga8-002 12249800-12301920 retained_intron
  ENSMUST00000148055 Itga8-006 12109070-12132552 protein_coding
  ENSMUST00000172716 Itga8-005 12219710-12242464 processed_transcript
  ENSMUST00000172791 Itga8-007 12107479-12301892 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000028106ENSMUST00000129370ENSMUST00000141477ENSMUST00000172791
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000028106 1.581±1.40 1.299±0.10 1.780±0.01 0.540±0.13 1.084±0.31 0.902±0.28 2.098±0.09 3.820±0.34 0.800±0.15 22.193±1.34 0.195±0.10 1.330±0.54 0.524±0.39 0.256±0.14
ENSMUST00000129370 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.815±0.00 1.891±1.54 N/A
ENSMUST00000141477 N/A 2.473±0.27 N/A N/A N/A N/A N/A N/A 0.434±0.08 N/A N/A N/A N/A N/A
ENSMUST00000172791 0.138±0.00 N/A N/A N/A N/A 0.454±0.00 N/A 0.701±0.00 0.323±0.00 N/A N/A 0.504±0.07 0.052±0.00 0.270±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00088I CIL_00088I_0002 VISTA 2:11765185-12368019
CIL_0002HM CIL_0002HM_0002 CGP 2:12106632-12419469

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001656 IGI metanephros development
GO:0001822 IEA kidney development
GO:0005783 IEA endoplasmic reticulum
GO:0005886 TAS plasma membrane
GO:0005925 IEA focal adhesion
GO:0007155 IEA cell adhesion
GO:0007160 IEA cell-matrix adhesion
GO:0007229 IEA integrin-mediated signaling pathway
GO:0007420 IEA brain development
GO:0007613 IMP memory
GO:0008305 IEA integrin complex
GO:0009986 IEA cell surface
GO:0014069 IEA postsynaptic density
GO:0030030 IMP cell projection organization
GO:0030198 IMP extracellular matrix organization
GO:0030511 IGI positive regulation of transforming growth factor beta receptor signaling pathway
GO:0032591 IEA dendritic spine membrane
GO:0034446 IEA substrate adhesion-dependent cell spreading
GO:0042472 IMP inner ear morphogenesis
GO:0043204 IEA perikaryon
GO:0045177 IDA apical part of cell
GO:0045184 IMP establishment of protein localization
GO:0046872 IEA metal ion binding
GO:0048333 IEA mesodermal cell differentiation
GO:0048745 IMP smooth muscle tissue development
GO:2000721 IDA positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078717 itga8 integrin, alpha 8 protein_coding Danio_rerio
ENSG00000077943 ITGA8 integrin, alpha 8 protein_coding Homo_sapiens

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