C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: methylcrotonoyl-CoA carboxylase 1 (alpha)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000078070 MCCC1 9606 - 3:183015218-183116075 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000265594 MCCC1-001 183015218-183099587 protein_coding
  ENST00000464601 MCCC1-012 183015289-183022717 retained_intron
  ENST00000466650 MCCC1-007 183071048-183099530 nonsense_mediated_decay
  ENST00000473955 MCCC1-013 183092373-183094607 retained_intron
  ENST00000476176 MCCC1-003 183020170-183099550 protein_coding
  ENST00000486226 MCCC1-010 183072427-183099495 nonsense_mediated_decay
  ENST00000487634 MCCC1-009 183071046-183099518 nonsense_mediated_decay
  ENST00000489909 MCCC1-011 183022469-183037355 processed_transcript
  ENST00000490284 MCCC1-008 183071006-183099523 nonsense_mediated_decay
  ENST00000492597 MCCC1-002 183015218-183116075 protein_coding
  ENST00000495767 MCCC1-004 183015551-183099518 nonsense_mediated_decay
  ENST00000497830 MCCC1-005 183015220-183099530 nonsense_mediated_decay
  ENST00000497959 MCCC1-006 183015289-183099243 nonsense_mediated_decay
  ENST00000539926 MCCC1-201 183015220-183099460 protein_coding
  ENST00000610757 MCCC1-202 183015220-183099577 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000265594ENST00000464601ENST00000476176ENST00000487634ENST00000490284ENST00000492597ENST00000495767ENST00000497830ENST00000539926ENST00000610757
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000265594 2.046±0.00 N/A 4.960±0.00 3.809±1.18 6.238±3.80 1.580±0.62 6.196±2.63 8.864±0.37 5.754±0.74 3.703±0.15 0.874±0.00 4.583±2.51 3.070±1.40 4.027±2.38
ENST00000464601 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.856±0.00 N/A N/A N/A
ENST00000476176 N/A N/A N/A N/A 2.427±0.00 1.461±0.00 1.489±0.00 6.342±0.00 1.811±0.00 5.075±0.00 0.912±0.00 3.959±0.00 N/A N/A
ENST00000487634 N/A N/A N/A N/A N/A 4.746±0.00 N/A N/A N/A N/A 9.412±0.00 10.242±0.00 N/A N/A
ENST00000490284 N/A N/A N/A 6.977±0.00 5.854±0.00 N/A N/A 16.591±0.00 N/A 10.626±0.00 N/A N/A N/A 10.608±0.00
ENST00000492597 N/A 1.737±0.00 N/A 1.608±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000495767 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.355±0.00 N/A N/A N/A
ENST00000497830 N/A N/A N/A 4.109±0.00 4.366±0.00 1.557±0.00 N/A N/A N/A N/A N/A 2.934±0.45 0.729±0.00 2.849±0.00
ENST00000539926 N/A N/A N/A N/A N/A 1.631±0.00 N/A 7.296±0.00 5.435±0.00 N/A 2.454±0.00 6.317±0.00 N/A 4.140±0.00
ENST00000610757 3.152±0.00 4.071±0.00 N/A N/A N/A 1.286±0.00 2.393±0.00 N/A 2.252±0.00 N/A N/A N/A N/A 2.397±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005FZ CIL_0005FZ_0001 CGP 3:182938074-183116075

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004075 IEA biotin carboxylase activity
GO:0004485 NAS methylcrotonoyl-CoA carboxylase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005739 IDA mitochondrion
GO:0005743 IEA mitochondrial inner membrane
GO:0005759 NAS mitochondrial matrix
GO:0005829 TAS cytosol
GO:0006552 IEA leucine catabolic process
GO:0006766 TAS vitamin metabolic process
GO:0006767 TAS water-soluble vitamin metabolic process
GO:0006768 NAS biotin metabolic process
GO:0008152 IEA metabolic process
GO:0008716 IEA D-alanine-D-alanine ligase activity
GO:0009083 TAS branched-chain amino acid catabolic process
GO:0009374 NAS biotin binding
GO:0016874 IEA ligase activity
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000054046 mccc1 methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) protein_coding Danio_rerio
ENSMUSG00000027709 Mccc1 methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) protein_coding Mus_musculus

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