C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dopachrome tautomerase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000080166 DCT 9606 - 13:94436808-94479682 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000377028 DCT-001 94436808-94479669 protein_coding
  ENST00000446125 DCT-201 94439589-94479682 protein_coding
  ENST00000472871 DCT-002 94465457-94479669 retained_intron
  ENST00000483392 DCT-003 94439487-94468770 nonsense_mediated_decay
  ENST00000490854 DCT-004 94462121-94467955 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000377028ENST00000446125ENST00000472871ENST00000483392ENST00000490854
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000377028 0.040±0.00 N/A 0.237±0.08 0.029±0.00 0.040±0.00 N/A 0.046±0.04 N/A 0.103±0.06 0.032±0.00 0.094±0.05 0.008±0.00 0.128±0.00
ENST00000446125 0.052±0.00 0.204±0.00 0.096±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.115±0.00
ENST00000472871 N/A N/A 0.159±0.00 0.008±0.00 0.092±0.00 0.044±0.00 N/A 0.058±0.00 N/A 0.110±0.00 N/A N/A N/A
ENST00000483392 N/A N/A 0.150±0.00 0.243±0.00 0.028±0.00 N/A N/A 0.169±0.00 N/A N/A 0.128±0.00 N/A 0.296±0.09
ENST00000490854 0.148±0.00 N/A N/A N/A N/A N/A N/A N/A 0.097±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000E8 CIL_0000E8_0001 CGP 13:93226842-94479682
CIL_000890 CIL_000890_0001 VISTA 13:94361598-94963187
CIL_0008KC CIL_0008KC_0001 VISTA 13:94406009-95007763
CIL_0000E7 CIL_0000E7_0001 CGP 13:94436808-94596257

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002052 IEA positive regulation of neuroblast proliferation
GO:0004167 ISS dopachrome isomerase activity
GO:0005507 TAS copper ion binding
GO:0005737 IEA cytoplasm
GO:0005829 ISS cytosol
GO:0006583 ISS melanin biosynthetic process from tyrosine
GO:0008152 IEA metabolic process
GO:0008544 TAS epidermis development
GO:0016021 IEA integral component of membrane
GO:0016491 IEA oxidoreductase activity
GO:0021847 IEA ventricular zone neuroblast division
GO:0042438 IEA melanin biosynthetic process
GO:0042470 ISS melanosome
GO:0043473 IEA pigmentation
GO:0048066 IEA developmental pigmentation
GO:0048468 IEA cell development
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006008 dct dopachrome tautomerase protein_coding Danio_rerio
ENSMUSG00000022129 Dct dopachrome tautomerase protein_coding Mus_musculus

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