C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: heat shock protein 90kDa alpha (cytosolic), class A member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000080824 HSP90AA1 9606 - 14:102080738-102139699 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000216281 HSP90AA1-002 102080738-102087191 protein_coding
  ENST00000334701 HSP90AA1-001 102081049-102139686 protein_coding
  ENST00000553585 HSP90AA1-005 102084933-102087044 protein_coding
  ENST00000554401 HSP90AA1-003 102082665-102086331 nonsense_mediated_decay
  ENST00000555662 HSP90AA1-006 102084980-102085707 retained_intron
  ENST00000556554 HSP90AA1-004 102085886-102087044 retained_intron
  ENST00000557089 HSP90AA1-007 102083442-102084234 retained_intron
  ENST00000557234 HSP90AA1-008 102085919-102139465 nonsense_mediated_decay
  ENST00000558600 HSP90AA1-010 102101938-102139699 processed_transcript
  ENST00000560130 HSP90AA1-009 102083896-102084798 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000216281ENST00000334701
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000216281 24.463±0.00 49.180±0.00 20.389±0.00 58.978±6.54 91.112±18.94 74.420±20.26 27.539±10.55 71.310±15.36 37.946±8.95 79.869±2.16 22.072±8.35 101.449±58.47 78.322±3.91 122.602±0.00
ENST00000334701 N/A N/A N/A 41.922±21.47 N/A N/A N/A N/A N/A N/A N/A 43.712±33.34 N/A 220.816±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001G1 CIL_0001G1_0001 CGP 14:102080738-102224847

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000086 TAS G2/M transition of mitotic cell cycle
GO:0000166 TAS nucleotide binding
GO:0000278 TAS mitotic cell cycle
GO:0005515 IPI protein binding
GO:0005524 TAS:IEA ATP binding
GO:0005576 TAS extracellular region
GO:0005622 IEA intracellular
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005829 NAS cytosol
GO:0005886 TAS plasma membrane
GO:0006200 IDA ATP catabolic process
GO:0006457 IEA protein folding
GO:0006839 TAS mitochondrial transport
GO:0006950 IEA response to stress
GO:0006986 NAS response to unfolded protein
GO:0007165 NAS signal transduction
GO:0007411 TAS axon guidance
GO:0016020 IDA membrane
GO:0016887 IDA ATPase activity
GO:0023026 IDA MHC class II protein complex binding
GO:0030235 IDA nitric-oxide synthase regulator activity
GO:0030911 TAS TPR domain binding
GO:0038096 TAS Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0042026 TAS protein refolding
GO:0042802 IPI identical protein binding
GO:0042803 TAS protein homodimerization activity
GO:0044281 TAS small molecule metabolic process
GO:0044822 IDA poly(A) RNA binding
GO:0045040 IDA protein import into mitochondrial outer membrane
GO:0045087 TAS innate immune response
GO:0045429 ISS positive regulation of nitric oxide biosynthetic process
GO:0046209 TAS nitric oxide metabolic process
GO:0050790 IEA regulation of catalytic activity
GO:0050999 TAS regulation of nitric-oxide synthase activity
GO:0051082 IEA unfolded protein binding
GO:0051131 IDA chaperone-mediated protein complex assembly
GO:0070062 IDA extracellular vesicular exosome
GO:0071682 TAS endocytic vesicle lumen

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010478 hsp90aa1.1 heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1 protein_coding Danio_rerio
ENSMUSG00000021270 Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 protein_coding Mus_musculus

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