C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: heat shock protein 90, alpha (cytosolic), class A member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021270 Hsp90aa1 10090 - 12:110690605-110702728 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000021698 Hsp90aa1-002 110691028-110696289 protein_coding
  ENSMUST00000094361 Hsp90aa1-001 110690605-110696395 protein_coding
  ENSMUST00000124156 Hsp90aa1-005 110695270-110696258 protein_coding
  ENSMUST00000129005 Hsp90aa1-008 110692709-110693180 retained_intron
  ENSMUST00000134967 Hsp90aa1-007 110693660-110694292 retained_intron
  ENSMUST00000145255 Hsp90aa1-004 110694175-110695672 retained_intron
  ENSMUST00000149189 Hsp90aa1-003 110695286-110695951 protein_coding
  ENSMUST00000155242 Hsp90aa1-006 110694629-110702728 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000021698ENSMUST00000094361ENSMUST00000129005ENSMUST00000134967ENSMUST00000145255ENSMUST00000155242
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000021698 21.282±4.82 8.211±2.73 25.865±16.71 84.589±56.92 10.050±0.24 6.687±4.89 6.988±3.70 20.257±2.72 41.682±57.87 19.478±1.94 4.798±1.04 29.473±18.97 170.181±133.89 157.954±0.00
ENSMUST00000094361 17.447±0.00 5.194±2.21 21.438±11.13 78.336±0.00 9.978±1.42 9.019±1.15 8.484±1.20 20.891±0.22 24.658±26.33 N/A 2.695±0.76 23.119±6.50 114.267±57.90 156.560±9.35
ENSMUST00000129005 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 797.828±0.00 3003.670±1968.44 N/A
ENSMUST00000134967 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 214.659±0.00 N/A N/A
ENSMUST00000145255 N/A N/A N/A 917.703±0.00 N/A N/A N/A N/A N/A N/A N/A 577.012±0.00 1545.688±1120.99 2514.260±0.00
ENSMUST00000155242 12.104±0.00 11.309±3.67 N/A N/A 17.187±2.00 11.486±2.53 9.548±0.26 16.114±1.35 8.148±3.39 N/A N/A 33.776±11.00 N/A 126.035±6.11

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001G1 CIL_0001G1_0002 CGP 12:110690605-110795028

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001764 IEA neuron migration
GO:0002134 IEA UTP binding
GO:0002135 IEA CTP binding
GO:0003009 IEA skeletal muscle contraction
GO:0003729 IEA mRNA binding
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005622 IDA intracellular
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005829 TAS cytosol
GO:0006200 IEA ATP catabolic process
GO:0006457 IEA protein folding
GO:0006809 TAS nitric oxide biosynthetic process
GO:0006986 TAS response to unfolded protein
GO:0009408 IEA response to heat
GO:0009651 IEA response to salt stress
GO:0009986 IEA cell surface
GO:0010592 IEA positive regulation of lamellipodium assembly
GO:0010659 IEA cardiac muscle cell apoptotic process
GO:0016020 IEA membrane
GO:0016323 IEA basolateral plasma membrane
GO:0016324 IEA apical plasma membrane
GO:0016887 IEA ATPase activity
GO:0017098 IEA sulfonylurea receptor binding
GO:0019901 IEA protein kinase binding
GO:0019903 IEA protein phosphatase binding
GO:0023026 IEA MHC class II protein complex binding
GO:0030235 IDA nitric-oxide synthase regulator activity
GO:0030911 ISS TPR domain binding
GO:0031012 IEA extracellular matrix
GO:0031526 IEA brush border membrane
GO:0032564 IEA dATP binding
GO:0033160 IEA positive regulation of protein import into nucleus, translocation
GO:0042026 TAS protein refolding
GO:0042802 IEA identical protein binding
GO:0042803 IDA protein homodimerization activity
GO:0043005 IEA neuron projection
GO:0043025 IEA neuronal cell body
GO:0043234 IEA protein complex
GO:0043627 IEA response to estrogen
GO:0044325 IEA ion channel binding
GO:0044822 IEA poly(A) RNA binding
GO:0045040 IEA protein import into mitochondrial outer membrane
GO:0045429 IDA positive regulation of nitric oxide biosynthetic process
GO:0045585 TAS positive regulation of cytotoxic T cell differentiation
GO:0045793 IEA positive regulation of cell size
GO:0048471 IEA perinuclear region of cytoplasm
GO:0050790 IDA regulation of catalytic activity
GO:0051082 IEA:TAS unfolded protein binding
GO:0051131 IEA chaperone-mediated protein complex assembly
GO:0060452 IEA positive regulation of cardiac muscle contraction
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010478 hsp90aa1.1 heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1 protein_coding Danio_rerio
ENSG00000080824 HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 protein_coding Homo_sapiens

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