C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nuclear factor, erythroid 2-like 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000082641 NFE2L1 9606 + 17:48048329-48061487 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000357480 NFE2L1-003 48048370-48061479 protein_coding
  ENST00000361665 NFE2L1-006 48048773-48061480 protein_coding
  ENST00000362042 NFE2L1-001 48048359-48061480 protein_coding
  ENST00000536222 NFE2L1-009 48054710-48059653 protein_coding
  ENST00000577411 NFE2L1-024 48054481-48058461 protein_coding
  ENST00000577431 NFE2L1-014 48054920-48058307 protein_coding
  ENST00000579481 NFE2L1-012 48048782-48051074 processed_transcript
  ENST00000579537 NFE2L1-015 48054328-48056444 protein_coding
  ENST00000579889 NFE2L1-020 48048329-48051146 protein_coding
  ENST00000580037 NFE2L1-018 48055952-48058416 protein_coding
  ENST00000580050 NFE2L1-017 48054587-48056588 protein_coding
  ENST00000581319 NFE2L1-019 48058877-48060050 protein_coding
  ENST00000581441 NFE2L1-023 48049132-48051129 protein_coding
  ENST00000582155 NFE2L1-007 48054675-48059833 protein_coding
  ENST00000582574 NFE2L1-013 48048783-48051097 processed_transcript
  ENST00000583060 NFE2L1-022 48048607-48051041 processed_transcript
  ENST00000583210 NFE2L1-016 48054328-48058342 protein_coding
  ENST00000583378 NFE2L1-008 48054692-48059936 protein_coding
  ENST00000584137 NFE2L1-010 48048359-48051366 protein_coding
  ENST00000584634 NFE2L1-025 48054550-48058331 protein_coding
  ENST00000585062 NFE2L1-011 48048784-48051416 protein_coding
  ENST00000585291 NFE2L1-002 48048363-48061487 protein_coding
  ENST00000585299 NFE2L1-021 48048478-48051072 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000357480ENST00000361665ENST00000362042ENST00000577411ENST00000580037ENST00000583378ENST00000585291
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000357480 23.272±0.00 8.425±0.00 N/A 15.263±9.92 17.492±0.00 13.648±10.94 N/A 34.639±0.00 N/A 12.897±0.00 187.721±0.00 47.164±4.00 39.702±0.97 25.245±17.66
ENST00000361665 23.867±0.00 15.184±0.00 4.865±0.00 N/A 40.702±0.00 19.352±17.95 8.096±0.00 29.571±0.00 6.384±3.46 8.140±6.36 118.990±105.65 13.422±1.08 13.790±1.61 23.775±0.00
ENST00000362042 N/A 15.186±0.00 9.902±0.00 3.143±0.00 15.267±0.00 11.894±8.74 35.422±31.79 N/A 7.861±0.86 6.478±1.96 N/A 13.743±9.14 24.273±10.47 22.358±0.00
ENST00000577411 N/A N/A N/A N/A 16.443±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000580037 N/A N/A N/A N/A N/A N/A N/A N/A N/A 14.125±0.00 N/A N/A N/A N/A
ENST00000583378 N/A N/A N/A 4.108±0.00 N/A 4.201±0.00 N/A N/A N/A N/A N/A 20.378±12.27 N/A 22.986±0.00
ENST00000585291 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 20.788±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007RQ CIL_0007RQ_0001 VISTA 17:47700006-48306250
CIL_0007WA CIL_0007WA_0001 VISTA 17:47751636-48352675
CIL_00097B CIL_00097B_0001 VISTA 17:47849190-48450331
CIL_0004MY CIL_0004MY_0002 CGP 17:48048329-48101521

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000980 IEA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001190 IEA RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription
GO:0001205 IEA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003712 TAS transcription cofactor activity
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005783 IEA endoplasmic reticulum
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006783 TAS heme biosynthetic process
GO:0006954 TAS inflammatory response
GO:0009653 TAS anatomical structure morphogenesis
GO:0016021 IEA integral component of membrane
GO:0030218 IEA erythrocyte differentiation
GO:0043565 IEA sequence-specific DNA binding
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076533 nfe2l1b nuclear factor, erythroid derived 2,-like 1b protein_coding Danio_rerio
ENSMUSG00000038615 Nfe2l1 nuclear factor, erythroid derived 2,-like 1 protein_coding Mus_musculus

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