C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nuclear factor, erythroid derived 2,-like 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000038615 Nfe2l1 10090 - 11:96817414-96829968 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000081775 Nfe2l1-201 96817414-96829968 protein_coding
  ENSMUST00000107657 Nfe2l1-002 96818182-96829955 protein_coding
  ENSMUST00000107658 Nfe2l1-001 96817431-96827955 protein_coding
  ENSMUST00000107659 Nfe2l1-008 96817599-96827719 protein_coding
  ENSMUST00000126949 Nfe2l1-005 96820093-96824127 protein_coding
  ENSMUST00000134951 Nfe2l1-007 96821346-96822725 processed_transcript
  ENSMUST00000135836 Nfe2l1-003 96827733-96829501 processed_transcript
  ENSMUST00000140138 Nfe2l1-004 96822223-96824552 processed_transcript
  ENSMUST00000142065 Nfe2l1-006 96820470-96824008 protein_coding
  ENSMUST00000167110 Nfe2l1-202 96817414-96824013 protein_coding
  ENSMUST00000167149 Nfe2l1-203 96817414-96829502 protein_coding
  ENSMUST00000169828 Nfe2l1-204 96817414-96824127 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000081775ENSMUST00000107657ENSMUST00000107658ENSMUST00000107659ENSMUST00000126949ENSMUST00000134951ENSMUST00000135836ENSMUST00000142065ENSMUST00000167110ENSMUST00000167149ENSMUST00000169828
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000081775 N/A 21.884±0.77 16.873±2.70 13.918±6.27 N/A 7.766±1.60 N/A 10.553±1.40 5.575±1.90 12.734±4.77 N/A 16.851±4.41 14.839±3.40 3.342±1.28
ENSMUST00000107657 16.138±1.90 64.484±4.12 9.662±2.46 19.674±15.25 15.562±1.15 13.545±4.46 19.474±1.72 14.386±0.03 4.332±0.64 15.115±3.79 N/A 19.266±10.77 16.580±7.20 4.198±1.52
ENSMUST00000107658 14.000±0.00 N/A 9.589±0.00 N/A N/A N/A 15.639±0.00 N/A 2.571±0.56 N/A 59.730±13.69 22.726±0.00 35.932±4.26 2.807±0.33
ENSMUST00000107659 45.074±7.92 82.828±10.68 N/A N/A 66.321±14.27 27.795±12.35 53.706±5.92 30.211±4.94 16.010±5.13 42.232±2.48 N/A 62.391±13.69 23.138±1.40 7.996±0.69
ENSMUST00000126949 N/A 166.217±8.29 N/A N/A N/A 40.720±0.00 N/A N/A N/A N/A N/A 81.950±0.00 N/A N/A
ENSMUST00000134951 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 96.683±0.00
ENSMUST00000135836 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 100.681±10.41 N/A
ENSMUST00000142065 N/A N/A N/A 381.056±0.00 N/A N/A N/A N/A N/A N/A N/A 526.031±0.00 254.397±4.83 N/A
ENSMUST00000167110 N/A N/A N/A N/A N/A N/A N/A 12.047±1.50 2.817±0.00 N/A N/A N/A N/A 4.711±1.25
ENSMUST00000167149 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 86.803±13.38 49.376±5.97 N/A N/A
ENSMUST00000169828 51.640±17.97 32.977±8.17 22.605±2.60 16.277±2.64 48.374±8.68 22.506±7.82 44.218±16.95 31.787±5.28 11.705±4.70 30.903±8.74 N/A 36.495±8.81 15.667±1.56 4.179±0.82

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00097B CIL_00097B_0002 VISTA 11:96441475-97042608
CIL_0007WA CIL_0007WA_0002 VISTA 11:96526222-97127190
CIL_0007RQ CIL_0007RQ_0002 VISTA 11:96583318-97187851

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000980 IDA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001190 IDA RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription
GO:0001205 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005783 IEA endoplasmic reticulum
GO:0016021 IEA integral component of membrane
GO:0030218 IMP erythrocyte differentiation
GO:0043565 IEA sequence-specific DNA binding
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076533 nfe2l1b nuclear factor, erythroid derived 2,-like 1b protein_coding Danio_rerio
ENSG00000082641 NFE2L1 nuclear factor, erythroid 2-like 1 protein_coding Homo_sapiens

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