C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: apolipoprotein B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000084674 APOB 9606 - 2:21001429-21044073 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000233242 APOB-001 21001429-21044073 protein_coding
  ENST00000399256 APOB-002 21024170-21043962 protein_coding
  ENST00000616098 APOB-201 21001429-21043945 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000233242ENST00000399256ENST00000616098
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000233242 N/A 0.008±0.00 0.190±0.00 0.025±0.00 2.386±0.00 N/A N/A 424.273±424.26 47.321±0.00 0.063±0.06 N/A 0.189±0.22 0.003±0.00 0.027±0.00
ENST00000399256 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.008±0.00 N/A N/A 0.005±0.00 N/A
ENST00000616098 3.143±0.00 0.037±0.00 N/A 0.064±0.04 0.471±0.00 0.136±0.02 1.305±0.83 0.029±0.00 249.261±0.00 0.003±0.00 0.190±0.05 0.100±0.04 0.003±0.00 0.079±0.05

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001523 TAS retinoid metabolic process
GO:0001701 IEA in utero embryonic development
GO:0005319 IEA lipid transporter activity
GO:0005488 IEA binding
GO:0005515 IPI protein binding
GO:0005543 IDA phospholipid binding
GO:0005576 TAS extracellular region
GO:0005615 ISS extracellular space
GO:0005737 IDA cytoplasm
GO:0005769 TAS early endosome
GO:0005783 IEA endoplasmic reticulum
GO:0005788 TAS endoplasmic reticulum lumen
GO:0005789 TAS endoplasmic reticulum membrane
GO:0005794 IDA Golgi apparatus
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0006629 IEA lipid metabolic process
GO:0006642 IEA triglyceride mobilization
GO:0006869 IEA lipid transport
GO:0006898 TAS receptor-mediated endocytosis
GO:0007283 IEA spermatogenesis
GO:0007399 IEA nervous system development
GO:0007596 TAS blood coagulation
GO:0007603 TAS phototransduction, visible light
GO:0008201 IDA heparin binding
GO:0008203 IMP cholesterol metabolic process
GO:0008289 IEA lipid binding
GO:0009566 IEA fertilization
GO:0009615 IEP response to virus
GO:0009743 IEA response to carbohydrate
GO:0009791 IEA post-embryonic development
GO:0010008 TAS endosome membrane
GO:0010033 IEA response to organic substance
GO:0010269 IEA response to selenium ion
GO:0010744 IDA positive regulation of macrophage derived foam cell differentiation
GO:0010884 IDA positive regulation of lipid storage
GO:0010886 IDA positive regulation of cholesterol storage
GO:0012506 IEA vesicle membrane
GO:0015629 IDA actin cytoskeleton
GO:0016042 IEA lipid catabolic process
GO:0017127 IMP cholesterol transporter activity
GO:0019433 IEA triglyceride catabolic process
GO:0030301 IMP cholesterol transport
GO:0030317 IEA sperm motility
GO:0030669 TAS clathrin-coated endocytic vesicle membrane
GO:0031904 TAS endosome lumen
GO:0031983 IEA vesicle lumen
GO:0032496 IEA response to lipopolysaccharide
GO:0033344 IEA cholesterol efflux
GO:0034359 IDA mature chylomicron
GO:0034360 TAS chylomicron remnant
GO:0034361 IDA very-low-density lipoprotein particle
GO:0034362 IDA low-density lipoprotein particle
GO:0034363 IDA intermediate-density lipoprotein particle
GO:0034374 IMP low-density lipoprotein particle remodeling
GO:0034379 IC very-low-density lipoprotein particle assembly
GO:0034383 IMP low-density lipoprotein particle clearance
GO:0035473 IPI lipase binding
GO:0042157 TAS lipoprotein metabolic process
GO:0042158 IEA lipoprotein biosynthetic process
GO:0042159 IEA lipoprotein catabolic process
GO:0042627 IDA chylomicron
GO:0042632 IMP cholesterol homeostasis
GO:0042953 IEA lipoprotein transport
GO:0043231 TAS intracellular membrane-bounded organelle
GO:0044281 TAS small molecule metabolic process
GO:0045540 IEA regulation of cholesterol biosynthetic process
GO:0048844 IEA artery morphogenesis
GO:0050750 IMP low-density lipoprotein particle receptor binding
GO:0050900 TAS leukocyte migration
GO:0070062 IDA extracellular vesicular exosome
GO:0071356 IEA cellular response to tumor necrosis factor
GO:0071379 IEA cellular response to prostaglandin stimulus
GO:0071682 TAS endocytic vesicle lumen

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000022767 apobb apolipoprotein Bb protein_coding Danio_rerio
ENSDARG00000042780 apoba apolipoprotein Ba protein_coding Danio_rerio
ENSDARG00000075016 apobl apolipoprotein B, like protein_coding Danio_rerio
ENSDARG00000093159 apolipoprotein B protein_coding Danio_rerio
ENSMUSG00000020609 Apob apolipoprotein B protein_coding Mus_musculus

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