C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: apolipoprotein B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020609 Apob 10090 + 12:7977648-8016835 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000037520 Apob-004 7977779-8016500 protein_coding
  ENSMUST00000037811 Apob-001 7977648-8016835 protein_coding
  ENSMUST00000171239 Apob-005 8012359-8016835 protein_coding
  ENSMUST00000171271 Apob-002 7977648-7987818 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000037520ENSMUST00000037811ENSMUST00000171239ENSMUST00000171271
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000037520 0.008±0.00 0.020±0.00 0.008±0.00 0.001±0.00 0.056±0.05 0.279±0.06 N/A N/A 3.563±0.00 N/A 0.014±0.00 0.050±0.06 12.012±10.84 0.012±0.01
ENSMUST00000037811 0.062±0.04 N/A 0.004±0.00 N/A 0.196±0.06 0.826±0.19 0.008±0.00 4.904±0.86 66.162±42.10 0.092±0.02 0.002±0.00 0.052±0.02 61.738±53.56 0.005±0.00
ENSMUST00000171239 0.011±0.00 0.129±0.02 0.029±0.00 0.097±0.00 0.709±0.17 1.521±0.41 0.056±0.04 8.625±0.83 164.348±87.13 0.133±0.03 0.033±0.02 0.257±0.19 163.436±182.61 0.015±0.01
ENSMUST00000171271 0.028±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.167±0.11 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007ID CIL_0007ID_0002 CGP 12:7977648-8285758

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001701 IMP in utero embryonic development
GO:0005319 IEA lipid transporter activity
GO:0005515 IEA protein binding
GO:0005543 IEA phospholipid binding
GO:0005576 TAS extracellular region
GO:0005615 IEA extracellular space
GO:0005737 IEA cytoplasm
GO:0005783 IDA endoplasmic reticulum
GO:0005794 IEA Golgi apparatus
GO:0005886 IEA plasma membrane
GO:0006629 IGI lipid metabolic process
GO:0006642 IMP triglyceride mobilization
GO:0007283 IMP spermatogenesis
GO:0007399 IMP nervous system development
GO:0008201 IEA heparin binding
GO:0008203 IEA cholesterol metabolic process
GO:0008289 IEA lipid binding
GO:0009566 IMP fertilization
GO:0009615 IEA response to virus
GO:0009743 IEA response to carbohydrate
GO:0009791 IMP post-embryonic development
GO:0010033 IEA response to organic substance
GO:0010269 IEA response to selenium ion
GO:0010744 IEA positive regulation of macrophage derived foam cell differentiation
GO:0010884 IEA positive regulation of lipid storage
GO:0010886 IEA positive regulation of cholesterol storage
GO:0012506 IEA vesicle membrane
GO:0015629 IEA actin cytoskeleton
GO:0016042 IMP lipid catabolic process
GO:0017127 IEA cholesterol transporter activity
GO:0019433 IMP triglyceride catabolic process
GO:0030301 IMP cholesterol transport
GO:0030317 IMP sperm motility
GO:0031983 IEA vesicle lumen
GO:0032496 IEA response to lipopolysaccharide
GO:0033344 IGI cholesterol efflux
GO:0034359 IEA mature chylomicron
GO:0034361 IEA very-low-density lipoprotein particle
GO:0034362 IEA low-density lipoprotein particle
GO:0034363 IEA intermediate-density lipoprotein particle
GO:0034374 IEA low-density lipoprotein particle remodeling
GO:0034383 IEA low-density lipoprotein particle clearance
GO:0035473 IEA lipase binding
GO:0042157 IMP lipoprotein metabolic process
GO:0042158 IGI lipoprotein biosynthetic process
GO:0042159 IGI lipoprotein catabolic process
GO:0042627 IEA chylomicron
GO:0042632 IGI cholesterol homeostasis
GO:0042953 IGI lipoprotein transport
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0045540 IMP regulation of cholesterol biosynthetic process
GO:0048844 IGI artery morphogenesis
GO:0050750 IEA low-density lipoprotein particle receptor binding
GO:0070062 IEA extracellular vesicular exosome
GO:0071356 IEA cellular response to tumor necrosis factor
GO:0071379 IEA cellular response to prostaglandin stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000022767 apobb apolipoprotein Bb protein_coding Danio_rerio
ENSDARG00000042780 apoba apolipoprotein Ba protein_coding Danio_rerio
ENSDARG00000075016 apobl apolipoprotein B, like protein_coding Danio_rerio
ENSDARG00000093159 apolipoprotein B protein_coding Danio_rerio
ENSG00000084674 APOB apolipoprotein B protein_coding Homo_sapiens

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