C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000084754 HADHA 9606 - 2:26190635-26244726 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000380649 HADHA-001 26190635-26244726 protein_coding
  ENST00000461025 HADHA-003 26232202-26235304 processed_transcript
  ENST00000471743 HADHA-002 26212097-26215093 retained_intron
  ENST00000492433 HADHA-004 26191335-26195169 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000380649ENST00000492433
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000380649 107.502±0.00 40.226±0.00 7.985±0.00 26.372±15.13 46.936±37.33 46.721±24.77 92.583±84.62 29.507±8.65 39.098±20.09 34.243±16.97 95.538±60.95 35.839±28.01 42.721±22.94 40.160±25.21
ENST00000492433 N/A N/A 19.569±0.00 8.532±0.00 N/A N/A N/A N/A 18.928±0.00 N/A 43.254±0.00 40.381±0.00 56.100±0.00 52.199±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007DH CIL_0007DH_0001 CGP 2:26173091-26244726
CIL_0007DK CIL_0007DK_0001 CGP 2:26190635-26290468

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000062 IEA fatty-acyl-CoA binding
GO:0003824 IEA catalytic activity
GO:0003857 TAS:IEA 3-hydroxyacyl-CoA dehydrogenase activity
GO:0003985 TAS acetyl-CoA C-acetyltransferase activity
GO:0003988 IEA acetyl-CoA C-acyltransferase activity
GO:0004300 IEA enoyl-CoA hydratase activity
GO:0005515 IPI protein binding
GO:0005739 IDA:IEA mitochondrion
GO:0005743 TAS mitochondrial inner membrane
GO:0006631 IEA fatty acid metabolic process
GO:0006635 IEA fatty acid beta-oxidation
GO:0006644 TAS phospholipid metabolic process
GO:0008152 IEA metabolic process
GO:0016491 IEA oxidoreductase activity
GO:0016507 IEA mitochondrial fatty acid beta-oxidation multienzyme complex
GO:0016508 IEA long-chain-enoyl-CoA hydratase activity
GO:0016509 IEA long-chain-3-hydroxyacyl-CoA dehydrogenase activity
GO:0032403 IEA protein complex binding
GO:0032868 IEA response to insulin
GO:0035965 TAS cardiolipin acyl-chain remodeling
GO:0042493 IEA response to drug
GO:0042645 IDA mitochondrial nucleoid
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046474 TAS glycerophospholipid biosynthetic process
GO:0050662 IEA coenzyme binding
GO:0051287 IEA NAD binding
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000057128 hadhaa hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase, alpha subunit a protein_coding Danio_rerio
ENSDARG00000060594 hadhab hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase, alpha subunit b protein_coding Danio_rerio
ENSMUSG00000025745 Hadha hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha su protein_coding Mus_musculus

Loading