C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000380649 HADHA-001 ENSG00000084754 9606 - 2:26190635-26244726 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000380649
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000380649 107.502±0.00 40.226±0.00 7.985±0.00 26.372±15.13 46.936±37.33 46.721±24.77 92.583±84.62 29.507±8.65 39.098±20.09 34.243±16.97 95.538±60.95 35.839±28.01 42.721±22.94 40.160±25.21

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007DH CIL_0007DH_0001 CGP 2:26173091-26244726
CIL_0007DK CIL_0007DK_0001 CGP 2:26190635-26290468

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000062 IEA fatty-acyl-CoA binding
GO:0003824 IEA catalytic activity
GO:0003857 TAS:IEA 3-hydroxyacyl-CoA dehydrogenase activity
GO:0003985 TAS acetyl-CoA C-acetyltransferase activity
GO:0003988 IEA acetyl-CoA C-acyltransferase activity
GO:0004300 IEA enoyl-CoA hydratase activity
GO:0005515 IPI protein binding
GO:0005739 IDA:IEA mitochondrion
GO:0005743 TAS mitochondrial inner membrane
GO:0006631 IEA fatty acid metabolic process
GO:0006635 IEA fatty acid beta-oxidation
GO:0006644 TAS phospholipid metabolic process
GO:0008152 IEA metabolic process
GO:0016491 IEA oxidoreductase activity
GO:0016507 IEA mitochondrial fatty acid beta-oxidation multienzyme complex
GO:0016508 IEA long-chain-enoyl-CoA hydratase activity
GO:0016509 IEA long-chain-3-hydroxyacyl-CoA dehydrogenase activity
GO:0032403 IEA protein complex binding
GO:0032868 IEA response to insulin
GO:0035965 TAS cardiolipin acyl-chain remodeling
GO:0042493 IEA response to drug
GO:0042645 IDA mitochondrial nucleoid
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046474 TAS glycerophospholipid biosynthetic process
GO:0051287 IEA NAD binding
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000156859 Hadha-001 protein_coding Mus_musculus 0 2519
ENSMUST00000026843 Hadha-004 processed_transcript Mus_musculus 0 2146
ENSMUST00000130358 Hadha-002 retained_intron Mus_musculus 0 1046
ENSMUST00000126081 Hadha-003 retained_intron Mus_musculus 0 634

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