C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ATP-binding cassette, sub-family B (MDR/TAP), member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000085563 ABCB1 9606 - 7:87503633-87713323 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000265724 ABCB1-001 87503859-87713248 protein_coding
  ENST00000416177 ABCB1-003 87585654-87713294 protein_coding
  ENST00000475929 ABCB1-009 87505902-87518963 processed_transcript
  ENST00000476862 ABCB1-004 87600813-87713295 processed_transcript
  ENST00000482527 ABCB1-005 87545949-87550158 retained_intron
  ENST00000483831 ABCB1-008 87516509-87521119 retained_intron
  ENST00000488737 ABCB1-007 87503864-87531697 processed_transcript
  ENST00000491360 ABCB1-010 87504156-87506141 retained_intron
  ENST00000496821 ABCB1-006 87515228-87537062 processed_transcript
  ENST00000543898 ABCB1-201 87503863-87713323 protein_coding
  ENST00000622132 ABCB1-202 87503633-87601073 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000265724ENST00000475929ENST00000482527ENST00000488737ENST00000496821ENST00000543898ENST00000622132
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000265724 0.694±0.00 N/A 7.962±0.00 2.404±0.16 2.014±1.60 1.992±1.61 0.383±0.00 5.202±1.33 1.350±0.28 1.043±0.36 N/A 0.786±0.34 1.305±0.18 0.690±0.00
ENST00000475929 0.938±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 1.543±0.00 1.138±0.00 N/A N/A N/A
ENST00000482527 N/A N/A N/A N/A N/A N/A 0.693±0.00 N/A N/A N/A 0.249±0.00 N/A N/A N/A
ENST00000488737 N/A N/A N/A N/A N/A N/A N/A N/A 2.463±0.00 N/A N/A N/A 1.071±0.21 0.755±0.00
ENST00000496821 N/A N/A N/A N/A 4.942±0.00 N/A N/A 5.277±0.00 N/A N/A N/A N/A N/A N/A
ENST00000543898 N/A N/A N/A N/A N/A 0.622±0.00 N/A N/A N/A N/A N/A 0.104±0.00 2.163±0.00 N/A
ENST00000622132 N/A 0.620±0.00 N/A 0.510±0.00 N/A N/A N/A N/A 1.961±0.00 N/A N/A N/A 1.012±0.00 0.881±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000086 IDA G2/M transition of mitotic cell cycle
GO:0005215 TAS transporter activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005886 TAS plasma membrane
GO:0006200 IEA ATP catabolic process
GO:0006810 TAS:IEA transport
GO:0006855 TAS drug transmembrane transport
GO:0008559 IEA xenobiotic-transporting ATPase activity
GO:0009986 IDA cell surface
GO:0016020 TAS membrane
GO:0016021 IBA:IEA integral component of membrane
GO:0016887 IEA ATPase activity
GO:0042493 TAS response to drug
GO:0042626 IBA:IEA ATPase activity, coupled to transmembrane movement of substances
GO:0042908 IEA xenobiotic transport
GO:0044281 TAS small molecule metabolic process
GO:0055085 IBA:IEA transmembrane transport
GO:0070062 IDA extracellular vesicular exosome
GO:0072089 IMP stem cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010936 abcb4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 protein_coding Danio_rerio
ENSMUSG00000028970 Abcb1b ATP-binding cassette, sub-family B (MDR/TAP), member 1B protein_coding Mus_musculus
ENSMUSG00000040584 Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A protein_coding Mus_musculus

Loading