C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ATP-binding cassette, sub-family B (MDR/TAP), member 1A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000040584 Abcb1a 10090 + 5:8660077-8748575 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000047753 Abcb1a-001 8660077-8748575 protein_coding
  ENSMUST00000126846 Abcb1a-002 8719819-8748570 retained_intron
  ENSMUST00000138138 Abcb1a-004 8733288-8737656 retained_intron
  ENSMUST00000145232 Abcb1a-003 8719849-8723174 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000047753ENSMUST00000126846ENSMUST00000138138
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000047753 3.748±0.98 1.141±0.25 0.952±0.00 2.639±2.15 1.455±0.46 35.489±9.38 1.889±0.85 1.553±0.22 0.608±0.27 5.363±1.36 1.587±0.76 2.503±0.76 6.230±3.58 0.571±0.11
ENSMUST00000126846 2.045±0.52 0.953±0.29 2.408±0.00 0.476±0.06 0.946±0.33 25.280±7.25 1.152±0.06 1.031±0.29 0.525±0.25 1.911±0.02 0.705±0.23 2.066±1.33 1.828±0.37 0.275±0.07
ENSMUST00000138138 N/A 1.663±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 IEA response to hypoxia
GO:0001890 IEA placenta development
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005886 TAS plasma membrane
GO:0006200 IEA ATP catabolic process
GO:0006855 IEA drug transmembrane transport
GO:0007595 IEA lactation
GO:0007623 IEA circadian rhythm
GO:0008559 IEA xenobiotic-transporting ATPase activity
GO:0009914 IEA hormone transport
GO:0014070 IEA response to organic cyclic compound
GO:0015893 IDA drug transport
GO:0016020 IEA membrane
GO:0016021 IBA integral component of membrane
GO:0031667 IEA response to nutrient levels
GO:0033280 IEA response to vitamin D
GO:0036146 IEA cellular response to mycotoxin
GO:0042493 IEA response to drug
GO:0042623 IDA ATPase activity, coupled
GO:0042626 IBA ATPase activity, coupled to transmembrane movement of substances
GO:0042908 IEA xenobiotic transport
GO:0043215 IEA daunorubicin transport
GO:0045177 IEA apical part of cell
GO:0046581 IDA intercellular canaliculus
GO:0046618 IEA drug export
GO:0046686 IEA response to cadmium ion
GO:0055085 IBA transmembrane transport
GO:0060548 IEA negative regulation of cell death
GO:0060856 IEA establishment of blood-brain barrier
GO:0071236 IEA cellular response to antibiotic
GO:0071312 IEA cellular response to alkaloid
GO:0071392 IEA cellular response to estradiol stimulus
GO:0071407 IEA cellular response to organic cyclic compound
GO:0071475 IEA cellular hyperosmotic salinity response
GO:0071548 IEA response to dexamethasone
GO:0071549 IEA cellular response to dexamethasone stimulus
GO:0097068 IEA response to thyroxine
GO:1902065 IEA response to L-glutamate
GO:2001025 IEA positive regulation of response to drug

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010936 abcb4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 protein_coding Danio_rerio
ENSG00000085563 ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 protein_coding Homo_sapiens

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