C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dynein, light chain, LC8-type 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000088986 DYNLL1 9606 + 12:120469850-120498493 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000242577 DYNLL1-001 120496056-120498493 protein_coding
  ENST00000392508 DYNLL1-003 120496091-120498491 protein_coding
  ENST00000392509 DYNLL1-006 120469850-120498493 protein_coding
  ENST00000548214 DYNLL1-007 120496082-120496896 protein_coding
  ENST00000548342 DYNLL1-004 120469883-120498237 protein_coding
  ENST00000549649 DYNLL1-005 120469857-120496547 protein_coding
  ENST00000549989 DYNLL1-008 120496113-120498350 protein_coding
  ENST00000550178 DYNLL1-010 120496101-120496681 protein_coding
  ENST00000550845 DYNLL1-002 120496113-120497673 protein_coding
  ENST00000552316 DYNLL1-011 120497824-120498493 processed_transcript
  ENST00000552870 DYNLL1-009 120496113-120498472 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000242577ENST00000392508ENST00000548214ENST00000549989ENST00000552870
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000242577 68.548±0.00 45.722±0.00 7.076±0.00 149.378±5.29 84.095±63.85 86.693±65.64 17.010±11.00 80.834±61.35 76.256±33.31 61.918±44.83 22.327±0.00 156.423±99.41 167.340±65.65 304.930±0.00
ENST00000392508 N/A 12.540±0.00 3.345±0.00 N/A 6.092±0.00 14.290±8.85 10.333±0.00 N/A 27.560±0.00 N/A 3.692±0.63 31.937±20.10 28.954±7.07 N/A
ENST00000548214 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.245±0.00 N/A N/A N/A
ENST00000549989 N/A N/A N/A 121.179±0.00 N/A 53.213±0.00 N/A 79.500±0.00 N/A 63.838±0.00 N/A 181.347±0.00 85.663±0.00 486.041±0.00
ENST00000552870 N/A N/A N/A N/A N/A N/A 1.954±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009CQ CIL_0009CQ_0001 VISTA 12:119991644-120595694
CIL_0007ZA CIL_0007ZA_0001 VISTA 12:120240385-120840841

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000086 TAS G2/M transition of mitotic cell cycle
GO:0000278 TAS mitotic cell cycle
GO:0000776 IDA kinetochore
GO:0003774 IEA motor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005813 IDA centrosome
GO:0005829 TAS cytosol
GO:0005856 IEA cytoskeleton
GO:0005868 ISS cytoplasmic dynein complex
GO:0005874 IEA microtubule
GO:0005875 IEA microtubule associated complex
GO:0005886 TAS plasma membrane
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006810 IEA transport
GO:0006915 TAS apoptotic process
GO:0007017 IEA microtubule-based process
GO:0007292 TAS female gamete generation
GO:0008022 IEA protein C-terminus binding
GO:0008180 IDA COP9 signalosome
GO:0009653 TAS anatomical structure morphogenesis
GO:0016020 IDA membrane
GO:0016032 IEA viral process
GO:0019886 TAS antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0019899 IEA enzyme binding
GO:0019904 IEA protein domain specific binding
GO:0021762 IEP substantia nigra development
GO:0030036 TAS actin cytoskeleton organization
GO:0030235 IEA nitric-oxide synthase regulator activity
GO:0042326 IDA negative regulation of phosphorylation
GO:0042803 IEA protein homodimerization activity
GO:0050790 IEA regulation of catalytic activity
GO:0070062 IDA extracellular vesicular exosome
GO:0072686 IDA mitotic spindle
GO:0097193 TAS intrinsic apoptotic signaling pathway
GO:1900740 TAS positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058454 dynll1 dynein, light chain, LC8-type 1 protein_coding Danio_rerio
ENSMUSG00000009013 Dynll1 dynein light chain LC8-type 1 protein_coding Mus_musculus

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