C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: baculoviral IAP repeat containing 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000089685 BIRC5 9606 + 17:78214186-78225636 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000301633 BIRC5-004 78214186-78225636 protein_coding
  ENST00000350051 BIRC5-001 78214198-78225636 protein_coding
  ENST00000374948 BIRC5-002 78214264-78225636 protein_coding
  ENST00000586192 BIRC5-009 78214385-78222979 nonsense_mediated_decay
  ENST00000587746 BIRC5-010 78214385-78222979 protein_coding
  ENST00000589892 BIRC5-012 78216427-78223856 processed_transcript
  ENST00000590449 BIRC5-003 78214280-78215099 protein_coding
  ENST00000590925 BIRC5-006 78214263-78223554 nonsense_mediated_decay
  ENST00000591800 BIRC5-011 78214385-78222979 nonsense_mediated_decay
  ENST00000592115 BIRC5-008 78214365-78222979 retained_intron
  ENST00000592734 BIRC5-005 78214317-78222992 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000301633ENST00000350051ENST00000374948ENST00000589892ENST00000590925ENST00000592115
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000301633 N/A 0.292±0.00 0.037±0.00 N/A N/A N/A 0.089±0.00 0.290±0.00 N/A 0.377±0.00 N/A 0.749±0.00 0.966±0.00 N/A
ENST00000350051 0.392±0.00 N/A N/A 0.046±0.00 0.429±0.00 2.168±0.00 N/A 0.170±0.00 0.064±0.00 N/A N/A 5.996±6.20 6.089±2.29 8.475±5.91
ENST00000374948 N/A 0.418±0.00 N/A N/A 0.391±0.00 0.425±0.00 0.055±0.00 N/A N/A N/A 0.047±0.00 1.673±0.00 N/A N/A
ENST00000589892 N/A N/A N/A N/A N/A N/A 0.030±0.00 N/A 0.210±0.00 0.350±0.00 N/A 9.049±0.00 3.996±0.00 7.752±0.00
ENST00000590925 N/A N/A N/A N/A 0.387±0.00 N/A N/A N/A N/A 0.520±0.00 N/A N/A N/A 7.701±0.00
ENST00000592115 N/A 0.210±0.00 0.179±0.00 0.083±0.01 0.195±0.01 N/A 0.098±0.00 N/A 0.046±0.01 0.575±0.00 0.134±0.12 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007YS CIL_0007YS_0001 VISTA 17:77940736-78544976
CIL_0006JS CIL_0006JS_0001 CGP 17:78187317-78225636
CIL_0003U8 CIL_0003U8_0002 CGP 17:78214186-78240987

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000086 IDA G2/M transition of mitotic cell cycle
GO:0000226 IEA microtubule cytoskeleton organization
GO:0000228 IDA nuclear chromosome
GO:0000278 TAS mitotic cell cycle
GO:0000775 IDA chromosome, centromeric region
GO:0000777 IDA condensed chromosome kinetochore
GO:0000910 IMP cytokinesis
GO:0004869 IEA cysteine-type endopeptidase inhibitor activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005814 IDA centriole
GO:0005829 IDA cytosol
GO:0005874 IEA microtubule
GO:0005876 IDA spindle microtubule
GO:0005881 IDA cytoplasmic microtubule
GO:0006351 IEA transcription, DNA-templated
GO:0006468 IDA protein phosphorylation
GO:0006915 IEA apoptotic process
GO:0007059 IEA chromosome segregation
GO:0007067 IEA mitotic nuclear division
GO:0007346 IEA regulation of mitotic cell cycle
GO:0008017 TAS microtubule binding
GO:0008270 IDA zinc ion binding
GO:0008284 TAS positive regulation of cell proliferation
GO:0008536 IPI Ran GTPase binding
GO:0010951 IEA negative regulation of endopeptidase activity
GO:0015631 IDA tubulin binding
GO:0019899 IPI enzyme binding
GO:0030496 IDA midbody
GO:0031021 IDA interphase microtubule organizing center
GO:0031503 IMP protein complex localization
GO:0031536 IMP positive regulation of exit from mitosis
GO:0031577 IMP spindle checkpoint
GO:0032133 IPI chromosome passenger complex
GO:0042802 IPI identical protein binding
GO:0042803 IDA protein homodimerization activity
GO:0043027 IMP cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0043066 IDA negative regulation of apoptotic process
GO:0043154 IDA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0045931 IMP positive regulation of mitotic cell cycle
GO:0046872 IEA metal ion binding
GO:0046982 IDA protein heterodimerization activity
GO:0048037 IDA cofactor binding
GO:0050897 NAS cobalt ion binding
GO:0051087 IPI chaperone binding
GO:0051301 IMP cell division
GO:0051303 IMP establishment of chromosome localization
GO:0061178 IEA regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0061469 IEA regulation of type B pancreatic cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075621 birc5a baculoviral IAP repeat-containing 5a protein_coding Danio_rerio
ENSMUSG00000017716 Birc5 baculoviral IAP repeat-containing 5 protein_coding Mus_musculus

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