C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cell division cycle 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000094804 CDC6 9606 + 17:40287633-40304657 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000209728 CDC6-001 40287633-40304657 protein_coding
  ENST00000473555 CDC6-002 40289192-40291234 protein_coding
  ENST00000577249 CDC6-004 40287907-40291181 protein_coding
  ENST00000580824 CDC6-003 40287902-40291555 protein_coding
  ENST00000582402 CDC6-005 40291467-40295506 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000209728ENST00000577249ENST00000580824ENST00000582402
Transcript ID Adipose Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000209728 0.104±0.00 0.412±0.31 0.131±0.00 0.280±0.00 0.101±0.08 0.306±0.00 0.081±0.06 0.126±0.00 0.102±0.00 4.543±5.90 2.671±1.82 2.994±0.84
ENST00000577249 0.339±0.00 N/A N/A N/A N/A N/A N/A 0.890±0.00 N/A N/A N/A N/A
ENST00000580824 N/A N/A 0.449±0.00 N/A N/A N/A 0.443±0.00 N/A N/A 4.926±0.00 2.180±0.00 N/A
ENST00000582402 N/A N/A N/A N/A N/A 1.498±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00098Y CIL_00098Y_0001 VISTA 17:39768583-40372873
CIL_0002GK CIL_0002GK_0001 CGP 17:40219304-40304657
CIL_0002GL CIL_0002GL_0001 CGP 17:40287633-40357643

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000076 TAS DNA replication checkpoint
GO:0000079 TAS regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000083 TAS regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0000166 TAS nucleotide binding
GO:0000278 TAS mitotic cell cycle
GO:0000922 IDA spindle pole
GO:0003682 IEA chromatin binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005794 IDA Golgi apparatus
GO:0005819 IEA spindle
GO:0005829 TAS cytosol
GO:0006260 TAS DNA replication
GO:0007067 IEA mitotic nuclear division
GO:0007089 TAS traversing start control point of mitotic cell cycle
GO:0008156 TAS negative regulation of DNA replication
GO:0008285 TAS negative regulation of cell proliferation
GO:0019900 IPI kinase binding
GO:0030071 IMP regulation of mitotic metaphase/anaphase transition
GO:0032467 IMP positive regulation of cytokinesis
GO:0051233 IDA spindle midzone
GO:0051984 IDA positive regulation of chromosome segregation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009942 cdc6 cell division cycle 6 homolog (S. cerevisiae) protein_coding Danio_rerio
ENSMUSG00000017499 Cdc6 cell division cycle 6 protein_coding Mus_musculus

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