C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: WW domain containing adaptor with coiled-coil
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000095787 WAC 9606 + 10:28532493-28623112 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000345541 WAC-003 28535686-28619960 retained_intron
  ENST00000347934 WAC-006 28533313-28620543 protein_coding
  ENST00000354911 WAC-017 28533419-28620543 protein_coding
  ENST00000375646 WAC-001 28532784-28619976 protein_coding
  ENST00000375664 WAC-016 28532493-28623112 protein_coding
  ENST00000414108 WAC-012 28534123-28595956 protein_coding
  ENST00000420266 WAC-004 28533506-28595870 protein_coding
  ENST00000424454 WAC-005 28533540-28610710 nonsense_mediated_decay
  ENST00000428935 WAC-201 28533540-28608433 protein_coding
  ENST00000439676 WAC-018 28535266-28619979 nonsense_mediated_decay
  ENST00000442148 WAC-010 28533749-28595777 protein_coding
  ENST00000448193 WAC-009 28533763-28583436 protein_coding
  ENST00000472862 WAC-019 28588737-28591833 retained_intron
  ENST00000476046 WAC-013 28595927-28608593 retained_intron
  ENST00000480474 WAC-014 28614999-28618041 retained_intron
  ENST00000495268 WAC-020 28608346-28611591 retained_intron
  ENST00000526722 WAC-024 28532773-28535726 protein_coding
  ENST00000528491 WAC-021 28532776-28535960 processed_transcript
  ENST00000530865 WAC-023 28533597-28535968 retained_intron
  ENST00000532233 WAC-022 28532779-28537664 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000345541ENST00000347934ENST00000354911ENST00000375646ENST00000375664
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000345541 N/A N/A N/A 4.233±0.00 2.287±0.00 N/A N/A N/A 4.342±0.00 N/A N/A N/A N/A
ENST00000347934 N/A 3.971±0.00 N/A N/A 7.494±3.95 N/A 14.314±0.00 N/A 9.993±0.00 N/A 26.979±17.53 21.614±13.83 47.823±0.00
ENST00000354911 20.798±0.00 9.885±0.00 19.175±1.05 11.475±0.59 23.271±13.47 11.592±4.60 9.766±0.00 18.671±12.67 14.103±9.04 7.610±4.77 15.492±6.81 8.357±3.34 24.049±5.16
ENST00000375646 N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.096±0.00 N/A N/A N/A
ENST00000375664 N/A 2.078±0.00 5.749±1.76 3.309±0.00 5.729±3.69 1.927±0.00 2.814±0.48 N/A 2.338±0.00 N/A 5.730±1.80 3.385±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00077T CIL_00077T_0002 CGP 10:28050993-28623112
CIL_0006FS CIL_0006FS_0002 CGP 10:28532493-28682939

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000993 IDA RNA polymerase II core binding
GO:0003682 IDA chromatin binding
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005681 IEA spliceosomal complex
GO:0006351 IEA transcription, DNA-templated
GO:0006974 IMP cellular response to DNA damage stimulus
GO:0010390 IMP histone monoubiquitination
GO:0016239 IMP positive regulation of macroautophagy
GO:0032435 IMP negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0044783 IMP G1 DNA damage checkpoint
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0071894 IMP histone H2B conserved C-terminal lysine ubiquitination

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000012577 waca WW domain containing adaptor with coiled-coil a protein_coding Danio_rerio
ENSDARG00000056403 wacb WW domain containing adaptor with coiled-coil b protein_coding Danio_rerio
ENSDARG00000086653 WAC (3 of 3) WW domain containing adaptor with coiled-coil protein_coding Danio_rerio
ENSMUSG00000024283 Wac WW domain containing adaptor with coiled-coil protein_coding Mus_musculus

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