C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: WW domain containing adaptor with coiled-coil
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024283 Wac 10090 + 18:7868832-7973547 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000074919 Wac-005 7868850-7927067 protein_coding
  ENSMUST00000092112 Wac-007 7869493-7927519 protein_coding
  ENSMUST00000165572 Wac-012 7869241-7871790 retained_intron
  ENSMUST00000165854 Wac-008 7871712-7921490 protein_coding
  ENSMUST00000166062 Wac-004 7869716-7916284 protein_coding
  ENSMUST00000166378 Wac-009 7868845-7871688 protein_coding
  ENSMUST00000167020 Wac-001 7869197-7929028 protein_coding
  ENSMUST00000167057 Wac-014 7910601-7916387 retained_intron
  ENSMUST00000167542 Wac-016 7910619-7918503 protein_coding
  ENSMUST00000168446 Wac-011 7869530-7916091 protein_coding
  ENSMUST00000169010 Wac-013 7869737-7905492 protein_coding
  ENSMUST00000169478 Wac-017 7917639-7973547 protein_coding
  ENSMUST00000170854 Wac-015 7905475-7916291 protein_coding
  ENSMUST00000170932 Wac-010 7869196-7871613 protein_coding
  ENSMUST00000171042 Wac-002 7868832-7926505 protein_coding
  ENSMUST00000171486 Wac-006 7869066-7926139 protein_coding
  ENSMUST00000172018 Wac-003 7869501-7926139 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000074919ENSMUST00000092112ENSMUST00000165572ENSMUST00000165854ENSMUST00000166062ENSMUST00000167020ENSMUST00000169478ENSMUST00000170854ENSMUST00000170932ENSMUST00000171042ENSMUST00000171486ENSMUST00000172018
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000074919 13.585±2.70 11.909±1.97 14.051±1.27 12.491±6.86 17.727±7.82 7.896±2.09 5.836±1.79 11.321±2.03 9.444±3.22 12.169±2.27 5.558±0.43 14.055±3.76 14.474±6.90 12.093±3.41
ENSMUST00000092112 5.574±1.57 N/A 6.802±0.63 7.537±1.73 8.667±4.02 4.819±0.00 3.589±0.98 5.975±1.12 5.457±1.09 8.881±2.65 1.649±0.49 9.698±1.95 11.361±2.69 7.818±0.97
ENSMUST00000165572 N/A 9.597±4.23 N/A N/A 13.210±0.00 11.759±1.78 N/A N/A N/A N/A N/A 19.800±3.50 N/A N/A
ENSMUST00000165854 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 25.001±0.82 N/A N/A
ENSMUST00000166062 N/A 15.303±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000167020 N/A N/A 2.490±0.32 5.362±0.18 N/A N/A N/A N/A 1.972±0.20 N/A 0.746±0.07 N/A N/A N/A
ENSMUST00000169478 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 25.684±0.00 N/A N/A
ENSMUST00000170854 N/A N/A N/A N/A N/A N/A N/A N/A 11.312±0.00 N/A N/A N/A N/A N/A
ENSMUST00000170932 N/A 22.438±5.86 N/A N/A N/A 24.143±8.02 N/A N/A N/A N/A N/A 30.375±4.57 N/A N/A
ENSMUST00000171042 N/A 13.966±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000171486 7.683±0.91 11.690±2.26 N/A N/A 6.498±0.00 N/A 4.076±0.00 N/A N/A N/A N/A 15.100±1.81 N/A N/A
ENSMUST00000172018 N/A N/A N/A N/A 17.669±0.00 N/A 3.758±0.00 4.969±0.12 4.364±0.00 N/A N/A N/A N/A 7.655±1.29

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00077T CIL_00077T_0003 CGP 18:7347962-7973547
CIL_0008UK CIL_0008UK_0002 VISTA 18:7743683-8345852

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000993 ISS RNA polymerase II core binding
GO:0003682 ISS chromatin binding
GO:0005634 IEA nucleus
GO:0005681 IDA spliceosomal complex
GO:0006351 IEA transcription, DNA-templated
GO:0006974 ISS cellular response to DNA damage stimulus
GO:0010390 ISS histone monoubiquitination
GO:0016239 IEA positive regulation of macroautophagy
GO:0032435 IEA negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0044783 ISS G1 DNA damage checkpoint
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0071894 ISS histone H2B conserved C-terminal lysine ubiquitination

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000012577 waca WW domain containing adaptor with coiled-coil a protein_coding Danio_rerio
ENSDARG00000056403 wacb WW domain containing adaptor with coiled-coil b protein_coding Danio_rerio
ENSDARG00000086653 WAC (3 of 3) WW domain containing adaptor with coiled-coil protein_coding Danio_rerio
ENSG00000095787 WAC WW domain containing adaptor with coiled-coil protein_coding Homo_sapiens

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