C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: heat shock protein 90kDa alpha (cytosolic), class B member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000096384 HSP90AB1 9606 + 6:44246166-44253888 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000353801 HSP90AB1-004 44247087-44253883 protein_coding
  ENST00000371554 HSP90AB1-005 44247866-44253883 protein_coding
  ENST00000371646 HSP90AB1-003 44247087-44253886 protein_coding
  ENST00000620073 HSP90AB1-201 44246166-44253888 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000371646
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000371646 239.388±0.00 227.062±0.00 42.753±0.00 284.949±84.29 175.160±52.79 314.328±247.52 118.215±45.32 162.427±103.35 101.490±16.70 262.720±173.26 198.761±122.79 346.328±100.91 223.354±67.36 232.737±93.39

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001890 IEA placenta development
GO:0002134 IEA UTP binding
GO:0002135 IEA CTP binding
GO:0003725 IDA double-stranded RNA binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005525 IEA GTP binding
GO:0005622 IEA intracellular
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005829 TAS cytosol
GO:0006457 IEA protein folding
GO:0006950 IEA response to stress
GO:0006986 NAS response to unfolded protein
GO:0007411 TAS axon guidance
GO:0008180 IDA COP9 signalosome
GO:0009651 IEA response to salt stress
GO:0009986 IEA cell surface
GO:0016020 IDA membrane
GO:0016234 IEA inclusion body
GO:0016323 IEA basolateral plasma membrane
GO:0016324 IEA apical plasma membrane
GO:0017098 IEA sulfonylurea receptor binding
GO:0019901 IEA protein kinase binding
GO:0023026 IDA MHC class II protein complex binding
GO:0030235 ISS nitric-oxide synthase regulator activity
GO:0030911 ISS TPR domain binding
GO:0031526 IEA brush border membrane
GO:0032092 IEA positive regulation of protein binding
GO:0032435 IMP negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032564 IEA dATP binding
GO:0033160 IEA positive regulation of protein import into nucleus, translocation
GO:0035872 TAS nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
GO:0038096 TAS Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0044325 IEA ion channel binding
GO:0044822 IDA poly(A) RNA binding
GO:0045087 TAS innate immune response
GO:0045429 ISS positive regulation of nitric oxide biosynthetic process
GO:0045793 IEA positive regulation of cell size
GO:0051082 IEA unfolded protein binding
GO:0060334 IMP regulation of interferon-gamma-mediated signaling pathway
GO:0060338 IMP regulation of type I interferon-mediated signaling pathway
GO:0070062 IDA extracellular vesicular exosome
GO:0071353 IEA cellular response to interleukin-4
GO:0071407 IEA cellular response to organic cyclic compound
GO:0071902 IEA positive regulation of protein serine/threonine kinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000023944 Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 protein_coding Mus_musculus

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