C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: heat shock protein 90 alpha (cytosolic), class B member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000023944 Hsp90ab1 10090 - 17:45567775-45573271 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000024739 Hsp90ab1-001 45567775-45573271 protein_coding
  ENSMUST00000130406 Hsp90ab1-002 45571538-45572555 protein_coding
  ENSMUST00000145205 Hsp90ab1-005 45568858-45569736 retained_intron
  ENSMUST00000146770 Hsp90ab1-004 45570445-45571582 retained_intron
  ENSMUST00000151306 Hsp90ab1-003 45571018-45573271 retained_intron
  ENSMUST00000163966 Hsp90ab1-007 45570663-45573255 nonsense_mediated_decay
  ENSMUST00000165127 Hsp90ab1-008 45569018-45573253 protein_coding
  ENSMUST00000166469 Hsp90ab1-006 45569578-45573255 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000024739ENSMUST00000163966ENSMUST00000166469
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000024739 263.849±103.46 188.466±22.19 319.167±37.24 360.235±69.70 187.179±11.18 144.916±9.15 240.883±16.08 171.925±9.75 253.660±122.99 178.667±25.33 282.723±6.09 421.190±267.39 753.463±588.95 80.389±45.94
ENSMUST00000163966 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 175.911±0.00 N/A N/A
ENSMUST00000166469 N/A N/A N/A 341.799±0.00 N/A N/A N/A N/A N/A N/A N/A 1013.470±0.00 788.253±535.74 264.537±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008DS CIL_0008DS_0002 VISTA 17:45025360-45628753

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001890 IMP placenta development
GO:0002134 IEA UTP binding
GO:0002135 IEA CTP binding
GO:0003725 ISO double-stranded RNA binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005525 IEA GTP binding
GO:0005622 IDA intracellular
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005829 IEA cytosol
GO:0006457 IEA protein folding
GO:0006950 IEA response to stress
GO:0008180 IEA COP9 signalosome
GO:0009651 IEA response to salt stress
GO:0009986 IEA cell surface
GO:0016020 IEA membrane
GO:0016234 IEA inclusion body
GO:0016323 IEA basolateral plasma membrane
GO:0016324 IEA apical plasma membrane
GO:0017098 IEA sulfonylurea receptor binding
GO:0019901 IEA protein kinase binding
GO:0023026 IEA MHC class II protein complex binding
GO:0030235 ISS nitric-oxide synthase regulator activity
GO:0030911 ISS TPR domain binding
GO:0031526 IEA brush border membrane
GO:0032092 IEA positive regulation of protein binding
GO:0032435 IEA negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032564 IEA dATP binding
GO:0033160 IEA positive regulation of protein import into nucleus, translocation
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0044325 IEA ion channel binding
GO:0044822 IEA poly(A) RNA binding
GO:0045429 ISS positive regulation of nitric oxide biosynthetic process
GO:0045793 IEA positive regulation of cell size
GO:0051082 IEA unfolded protein binding
GO:0060334 IEA regulation of interferon-gamma-mediated signaling pathway
GO:0060338 IEA regulation of type I interferon-mediated signaling pathway
GO:0070062 IEA extracellular vesicular exosome
GO:0071353 IDA cellular response to interleukin-4
GO:0071407 IEA cellular response to organic cyclic compound
GO:0071902 IEA positive regulation of protein serine/threonine kinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000096384 HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 protein_coding Homo_sapiens

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