C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: proline dehydrogenase (oxidase) 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100033 PRODH 9606 - 22:18912777-18936553 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000313755 PRODH-007 18912782-18921574 retained_intron
  ENST00000334029 PRODH-002 18912782-18936451 protein_coding
  ENST00000357068 PRODH-001 18912782-18936553 protein_coding
  ENST00000399694 PRODH-012 18922246-18923310 retained_intron
  ENST00000420436 PRODH-004 18912781-18936296 protein_coding
  ENST00000429300 PRODH-006 18912782-18924002 retained_intron
  ENST00000438924 PRODH-011 18921381-18936142 protein_coding
  ENST00000446371 PRODH-008 18919556-18921539 retained_intron
  ENST00000450579 PRODH-010 18922372-18934828 protein_coding
  ENST00000457083 PRODH-009 18922880-18936266 protein_coding
  ENST00000482858 PRODH-005 18912782-18936142 retained_intron
  ENST00000491604 PRODH-003 18912781-18936295 retained_intron
  ENST00000496625 PRODH-013 18924725-18931110 retained_intron
  ENST00000609229 PRODH-014 18914530-18921554 retained_intron
  ENST00000610940 PRODH-201 18912777-18936553 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000313755ENST00000429300ENST00000482858ENST00000491604ENST00000496625ENST00000609229
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000313755 N/A N/A N/A 0.430±0.00 N/A N/A N/A N/A N/A 0.775±0.00 N/A N/A 0.063±0.00 N/A
ENST00000429300 0.231±0.00 N/A N/A 1.553±1.21 N/A N/A 0.214±0.00 1.856±0.00 N/A N/A N/A 6.469±6.35 0.123±0.03 0.419±0.00
ENST00000482858 N/A N/A N/A 0.897±0.73 0.097±0.00 N/A 0.053±0.00 0.430±0.33 0.083±0.00 0.205±0.09 0.274±0.00 2.620±1.67 0.055±0.00 N/A
ENST00000491604 N/A N/A N/A N/A N/A N/A N/A N/A 0.022±0.00 N/A N/A N/A N/A N/A
ENST00000496625 N/A N/A N/A N/A N/A 0.287±0.00 N/A N/A N/A N/A N/A 5.027±0.00 N/A N/A
ENST00000609229 0.227±0.00 0.068±0.00 0.243±0.00 0.674±0.38 0.321±0.15 0.169±0.12 0.082±0.04 0.327±0.24 0.081±0.04 0.188±0.00 0.324±0.00 1.612±1.63 0.041±0.00 0.266±0.05

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005EQ CIL_0005EQ_0001 CGP 22:18906028-18936553

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004657 IEA proline dehydrogenase activity
GO:0005743 TAS mitochondrial inner membrane
GO:0006560 TAS proline metabolic process
GO:0006562 IEA proline catabolic process
GO:0008631 NAS intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0010133 IEA proline catabolic process to glutamate
GO:0019470 TAS 4-hydroxyproline catabolic process
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0055114 IEA oxidation-reduction process
GO:0071949 IDA FAD binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044804 prodha proline dehydrogenase (oxidase) 1a protein_coding Danio_rerio
ENSDARG00000086512 protein_coding Danio_rerio
ENSDARG00000086746 protein_coding Danio_rerio
ENSMUSG00000003526 Prodh proline dehydrogenase protein_coding Mus_musculus

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