C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100368 CSF2RB 9606 + 22:36913628-36940449 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262825 CSF2RB-201 36913633-36940433 protein_coding
  ENST00000403662 CSF2RB-001 36913628-36940449 protein_coding
  ENST00000406230 CSF2RB-002 36922134-36938611 protein_coding
  ENST00000421539 CSF2RB-003 36922612-36930744 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartLungMuscleOvaryPlacentaTestisENST00000262825ENST00000403662ENST00000406230ENST00000421539
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Lung Muscle Ovary Placenta Testis
ENST00000262825 0.330±0.00 N/A N/A N/A N/A N/A N/A N/A 0.163±0.00 N/A 2.836±0.00 0.244±0.00
ENST00000403662 2.233±0.00 34.469±0.00 0.031±0.00 0.670±0.00 0.790±0.20 1.328±0.00 0.273±0.00 3.003±0.67 N/A 0.618±0.65 23.646±19.76 N/A
ENST00000406230 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.344±0.00 N/A 1.496±0.00
ENST00000421539 N/A N/A 0.308±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003GY CIL_0003GY_0001 CGP 22:36860988-36940449
CIL_00036S CIL_00036S_0001 CGP 22:36913628-37007841

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004872 TAS receptor activity
GO:0004896 IEA cytokine receptor activity
GO:0004912 TAS interleukin-3 receptor activity
GO:0004914 TAS interleukin-5 receptor activity
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0005887 NAS integral component of plasma membrane
GO:0007165 NAS signal transduction
GO:0007585 TAS respiratory gaseous exchange
GO:0016021 IEA integral component of membrane
GO:0019221 IEA cytokine-mediated signaling pathway
GO:0030526 TAS granulocyte macrophage colony-stimulating factor receptor complex
GO:0032496 IEA response to lipopolysaccharide
GO:0036016 TAS cellular response to interleukin-3
GO:0038043 TAS interleukin-5-mediated signaling pathway
GO:0038156 TAS interleukin-3-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076586 csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) protein_coding Danio_rerio
ENSMUSG00000071713 Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) protein_coding Mus_musculus
ENSMUSG00000071714 Csf2rb2 colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) protein_coding Mus_musculus

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