C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ceramide kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100422 CERK 9606 - 22:46684411-46738261 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000216264 CERK-001 46684411-46738261 protein_coding
  ENST00000443629 CERK-002 46686983-46738207 nonsense_mediated_decay
  ENST00000460254 CERK-003 46735159-46738090 processed_transcript
  ENST00000471929 CERK-004 46690055-46693812 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000216264ENST00000443629
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000216264 9.137±0.00 6.057±0.00 2.212±0.00 11.520±3.56 5.506±0.00 5.274±3.36 11.988±8.77 14.234±0.00 3.762±2.15 11.263±0.00 5.700±0.00 10.016±5.45 5.648±0.69 6.835±0.06
ENST00000443629 N/A N/A 0.760±0.00 N/A N/A 3.353±0.00 2.361±0.00 1.097±0.00 2.661±0.00 2.187±0.00 3.114±0.00 2.656±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008BF CIL_0008BF_0001 VISTA 22:46352708-46954203
CIL_00024X CIL_00024X_0001 CGP 22:46576012-46738261
CIL_00025D CIL_00025D_0001 CGP 22:46684411-47175699

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 IDA magnesium ion binding
GO:0001729 IDA ceramide kinase activity
GO:0003951 IEA NAD+ kinase activity
GO:0004143 IEA diacylglycerol kinase activity
GO:0005524 IEA ATP binding
GO:0005739 IEA mitochondrion
GO:0005886 TAS plasma membrane
GO:0006665 TAS sphingolipid metabolic process
GO:0006672 TAS ceramide metabolic process
GO:0006687 TAS glycosphingolipid metabolic process
GO:0007205 IEA protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0008152 IEA metabolic process
GO:0016021 IDA integral component of membrane
GO:0016310 IEA phosphorylation
GO:0044281 TAS small molecule metabolic process
GO:0046834 IEA lipid phosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000069169 cerk ceramide kinase protein_coding Danio_rerio
ENSMUSG00000035891 Cerk ceramide kinase protein_coding Mus_musculus

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