C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ceramide kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000035891 Cerk 10090 - 15:86139128-86186141 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000044332 Cerk-001 86139129-86186141 protein_coding
  ENSMUST00000150767 Cerk-003 86139128-86159468 retained_intron
  ENSMUST00000156546 Cerk-002 86140321-86152448 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000044332ENSMUST00000150767ENSMUST00000156546
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000044332 4.668±1.48 7.740±1.67 2.656±1.23 5.825±0.61 8.674±2.33 9.414±2.22 5.693±0.43 4.199±0.82 1.297±0.87 8.871±2.61 1.062±0.33 7.994±3.14 3.603±1.14 12.629±5.09
ENSMUST00000150767 6.481±2.36 16.834±2.42 N/A 4.061±0.18 9.510±4.87 9.109±3.23 4.540±0.37 2.980±0.71 0.895±0.27 13.313±1.71 0.228±0.04 7.182±4.05 2.433±0.67 6.653±3.84
ENSMUST00000156546 N/A 6.349±0.00 N/A 3.144±0.00 7.993±1.39 N/A 4.121±0.86 3.560±0.57 0.641±0.12 6.130±0.00 0.450±0.00 N/A 2.142±0.00 10.201±0.89

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008BF CIL_0008BF_0002 VISTA 15:85812646-86415385
CIL_00024X CIL_00024X_0002 CGP 15:86057695-86186141
CIL_00025D CIL_00025D_0002 CGP 15:86139128-86498503

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 ISS magnesium ion binding
GO:0001729 ISO:ISS ceramide kinase activity
GO:0003951 IEA NAD+ kinase activity
GO:0004143 IEA diacylglycerol kinase activity
GO:0005524 IEA ATP binding
GO:0005739 IDA mitochondrion
GO:0006672 ISO:ISS ceramide metabolic process
GO:0007205 IEA protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0016020 ISA membrane
GO:0016021 ISS integral component of membrane
GO:0046834 ISO:IEA lipid phosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000069169 cerk ceramide kinase protein_coding Danio_rerio
ENSG00000100422 CERK ceramide kinase protein_coding Homo_sapiens

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