C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: histone deacetylase 10
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100429 HDAC10 9606 - 22:50245183-50251405 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000216271 HDAC10-001 50245183-50251385 protein_coding
  ENST00000349505 HDAC10-008 50245507-50251032 protein_coding
  ENST00000415993 HDAC10-002 50245183-50251261 nonsense_mediated_decay
  ENST00000429374 HDAC10-006 50245405-50251079 nonsense_mediated_decay
  ENST00000448072 HDAC10-005 50245442-50251240 protein_coding
  ENST00000454936 HDAC10-007 50245442-50251032 nonsense_mediated_decay
  ENST00000470378 HDAC10-018 50247908-50249203 retained_intron
  ENST00000470965 HDAC10-017 50249868-50251385 processed_transcript
  ENST00000471375 HDAC10-020 50246329-50249040 retained_intron
  ENST00000475965 HDAC10-010 50247138-50248455 retained_intron
  ENST00000476310 HDAC10-019 50247696-50249075 retained_intron
  ENST00000477814 HDAC10-009 50245450-50249208 retained_intron
  ENST00000482213 HDAC10-016 50250257-50250972 retained_intron
  ENST00000483222 HDAC10-004 50245442-50251242 processed_transcript
  ENST00000488270 HDAC10-014 50249287-50250255 retained_intron
  ENST00000489424 HDAC10-013 50249859-50251228 processed_transcript
  ENST00000496235 HDAC10-021 50245979-50248372 retained_intron
  ENST00000496909 HDAC10-012 50248695-50250890 processed_transcript
  ENST00000497483 HDAC10-011 50250119-50251405 processed_transcript
  ENST00000497952 HDAC10-015 50245791-50247948 retained_intron
  ENST00000498366 HDAC10-003 50245442-50251366 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000216271ENST00000349505ENST00000448072ENST00000470378ENST00000475965ENST00000476310ENST00000483222ENST00000497483ENST00000498366
Transcript ID Adipose Adrenal Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000216271 2.907±0.00 10.865±0.00 4.703±0.00 2.135±1.20 1.918±0.00 5.139±0.00 3.940±0.00 4.832±0.00 11.209±1.50 4.967±0.22 4.221±0.00
ENST00000349505 N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.351±0.33 N/A
ENST00000448072 N/A N/A N/A 0.406±0.00 N/A 0.414±0.00 N/A N/A N/A 3.746±0.00 N/A
ENST00000470378 N/A N/A N/A N/A N/A 0.698±0.00 N/A 1.013±0.00 N/A N/A N/A
ENST00000475965 N/A N/A 0.662±0.00 0.362±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000476310 N/A N/A N/A N/A N/A N/A 0.508±0.00 N/A N/A N/A N/A
ENST00000483222 N/A N/A N/A N/A N/A N/A N/A 0.527±0.00 N/A N/A N/A
ENST00000497483 N/A N/A N/A N/A N/A 2.167±0.00 N/A N/A N/A N/A N/A
ENST00000498366 N/A N/A 3.274±0.00 N/A N/A N/A 1.891±0.00 3.666±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000096 CIL_000096_0001 CGP 22:50217689-50251405
CIL_0006L4 CIL_0006L4_0001 CGP 22:50245183-50261825

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000118 IDA histone deacetylase complex
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0004407 IDA histone deacetylase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 IDA nucleoplasm
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006476 IDA protein deacetylation
GO:0007219 TAS Notch signaling pathway
GO:0008152 IEA metabolic process
GO:0014003 IEA oligodendrocyte development
GO:0016568 NAS chromatin modification
GO:0016575 IDA histone deacetylation
GO:0016787 IEA hydrolase activity
GO:0019899 IPI enzyme binding
GO:0032041 IEA NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0033558 IDA protein deacetylase activity
GO:0042826 IDA histone deacetylase binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0046969 IEA NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970 IEA NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:0070932 IEA histone H3 deacetylation
GO:0070933 IEA histone H4 deacetylation
GO:0097372 IEA NAD-dependent histone deacetylase activity (H3-K18 specific)

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000086458 hdac10 histone deacetylase 10 protein_coding Danio_rerio
ENSMUSG00000062906 Hdac10 histone deacetylase 10 protein_coding Mus_musculus

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