C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cyclin-dependent kinase inhibitor 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100526 CDKN3 9606 + 14:54396849-54420218 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000216414 CDKN3-005 54399889-54420116 processed_transcript
  ENST00000335183 CDKN3-001 54396955-54420218 protein_coding
  ENST00000395577 CDKN3-201 54408564-54420214 protein_coding
  ENST00000442975 CDKN3-003 54396995-54420212 protein_coding
  ENST00000458126 CDKN3-002 54397000-54420218 protein_coding
  ENST00000541304 CDKN3-004 54397029-54414219 protein_coding
  ENST00000543789 CDKN3-009 54396979-54417951 protein_coding
  ENST00000555837 CDKN3-008 54396849-54417951 processed_transcript
  ENST00000556102 CDKN3-010 54397003-54420218 protein_coding
  ENST00000556305 CDKN3-011 54399926-54418414 processed_transcript
  ENST00000611205 CDKN3-202 54396955-54420214 protein_coding
  ENST00000620759 CDKN3-203 54399888-54420116 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000216414ENST00000335183ENST00000395577ENST00000442975ENST00000458126ENST00000541304ENST00000543789ENST00000555837ENST00000556102ENST00000556305ENST00000611205ENST00000620759
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000216414 N/A N/A N/A N/A N/A 0.432±0.00 0.412±0.00 N/A N/A 7.651±0.00 4.750±0.00 62.574±0.00
ENST00000335183 1.165±0.00 N/A N/A 0.352±0.00 0.219±0.00 0.737±0.00 N/A N/A N/A 3.539±0.00 1.059±0.29 32.927±0.03
ENST00000395577 0.885±0.00 0.674±0.00 1.500±0.00 N/A 4.348±3.32 0.295±0.20 N/A N/A N/A 4.387±2.30 1.576±0.69 N/A
ENST00000442975 N/A N/A 1.620±0.00 1.406±0.00 N/A 0.332±0.00 N/A N/A N/A 1.177±0.00 N/A 38.850±0.00
ENST00000458126 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.869±0.00 N/A 12.985±0.00
ENST00000541304 N/A N/A N/A N/A N/A N/A 0.055±0.00 N/A N/A N/A N/A N/A
ENST00000543789 N/A N/A 0.738±0.21 1.514±0.00 1.522±0.00 0.268±0.00 0.403±0.00 N/A N/A 0.657±0.00 N/A N/A
ENST00000555837 0.695±0.00 1.415±0.00 0.706±0.18 0.980±0.31 0.659±0.00 N/A 0.303±0.00 0.080±0.00 0.215±0.00 1.456±0.42 0.458±0.00 30.451±0.00
ENST00000556102 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.733±0.00 N/A N/A
ENST00000556305 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.417±0.39 N/A N/A
ENST00000611205 N/A 1.253±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000620759 N/A N/A N/A N/A N/A N/A N/A 0.109±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008KQ CIL_0008KQ_0001 VISTA 14:53920865-54521777
CIL_00090Z CIL_00090Z_0001 VISTA 14:53923660-54524764
CIL_0005GF CIL_0005GF_0001 CGP 14:53949736-54420218
CIL_0000HQ CIL_0000HQ_0001 CGP 14:54396849-54441431

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000079 TAS regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0004721 IEA phosphoprotein phosphatase activity
GO:0004722 IDA protein serine/threonine phosphatase activity
GO:0004725 IDA:IEA protein tyrosine phosphatase activity
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0006470 IEA protein dephosphorylation
GO:0007050 IDA cell cycle arrest
GO:0008138 TAS:IEA protein tyrosine/serine/threonine phosphatase activity
GO:0008285 TAS negative regulation of cell proliferation
GO:0016311 IEA dephosphorylation
GO:0016791 IEA phosphatase activity
GO:0035335 IEA peptidyl-tyrosine dephosphorylation
GO:0048471 IDA perinuclear region of cytoplasm

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039130 cdkn3 cyclin-dependent kinase inhibitor 3 protein_coding Danio_rerio
ENSMUSG00000037628 Cdkn3 cyclin-dependent kinase inhibitor 3 protein_coding Mus_musculus

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