C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: p21 protein (Cdc42/Rac)-activated kinase 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000101349 PAK7 9606 - 20:9537389-9839041 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000353224 PAK7-002 9537389-9838867 protein_coding
  ENST00000378423 PAK7-003 9537389-9838831 protein_coding
  ENST00000378429 PAK7-001 9537389-9839041 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000353224ENST00000378423ENST00000378429
Transcript ID Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000353224 0.103±0.00 2.931±0.44 0.201±0.00 0.015±0.01 N/A 0.066±0.06 0.018±0.00 0.040±0.01 0.044±0.05 0.068±0.06 0.134±0.00
ENST00000378423 N/A N/A N/A N/A 0.005±0.00 0.011±0.00 N/A N/A 0.001±0.00 N/A 0.165±0.00
ENST00000378429 N/A 0.967±0.20 N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00035V CIL_00035V_0001 CGP 20:9514358-9839041
CIL_00017Y CIL_00017Y_0001 CGP 20:9537389-10058303

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005739 IEA mitochondrion
GO:0006468 IEA protein phosphorylation
GO:0006915 TAS apoptotic process
GO:0007010 TAS cytoskeleton organization
GO:0007165 TAS signal transduction
GO:0007612 IEA learning
GO:0007613 IEA memory
GO:0007626 IEA locomotory behavior
GO:0008283 TAS cell proliferation
GO:0016049 TAS cell growth
GO:0016477 TAS cell migration
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:2001237 IEA negative regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000030154 PAK7 (1 of 2) p21 protein (Cdc42/Rac)-activated kinase 7 protein_coding Danio_rerio
ENSDARG00000079437 pak7 p21(CDKN1A)-activated kinase 7 protein_coding Danio_rerio
ENSMUSG00000039913 Pak7 p21 protein (Cdc42/Rac)-activated kinase 7 protein_coding Mus_musculus

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