C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: p21 protein (Cdc42/Rac)-activated kinase 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000039913 Pak7 10090 - 2:136081104-136387967 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000035264 Pak7-001 136081104-136387938 protein_coding
  ENSMUST00000077200 Pak7-002 136081897-136387960 protein_coding
  ENSMUST00000143329 Pak7-003 136267695-136387967 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000035264ENSMUST00000077200ENSMUST00000143329
Transcript ID Adipose Adrenal Bladder Brain Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000035264 N/A N/A 0.006±0.00 2.852±1.35 N/A N/A N/A 0.011±0.01 0.038±0.00 N/A N/A 0.006±0.00 N/A
ENSMUST00000077200 0.059±0.00 0.023±0.00 0.019±0.00 4.507±1.96 0.032±0.01 0.060±0.02 0.019±0.00 0.009±0.01 0.012±0.00 0.008±0.00 0.205±0.12 0.013±0.00 0.120±0.02
ENSMUST00000143329 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.009±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00035V CIL_00035V_0002 CGP 2:136052239-136387967
CIL_00017Y CIL_00017Y_0002 CGP 2:136081104-136562091

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004674 IDA protein serine/threonine kinase activity
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005739 IDA mitochondrion
GO:0006468 IEA protein phosphorylation
GO:0006915 IEA apoptotic process
GO:0007010 IEA cytoskeleton organization
GO:0007612 IGI learning
GO:0007613 IGI memory
GO:0007626 IGI locomotory behavior
GO:0016049 IEA cell growth
GO:2001237 IDA negative regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000030154 PAK7 (1 of 2) p21 protein (Cdc42/Rac)-activated kinase 7 protein_coding Danio_rerio
ENSDARG00000079437 pak7 p21(CDKN1A)-activated kinase 7 protein_coding Danio_rerio
ENSG00000101349 PAK7 p21 protein (Cdc42/Rac)-activated kinase 7 protein_coding Homo_sapiens

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