C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: syntrophin, alpha 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000101400 SNTA1 9606 - 20:33407955-33443892 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000217381 SNTA1-001 33407955-33443892 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000217381
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000217381 28.385±0.00 18.864±0.00 1.557±0.00 32.246±21.37 18.125±17.51 10.950±9.31 48.669±41.13 7.635±6.81 4.976±0.06 3.224±2.82 84.691±54.68 13.277±11.34 5.158±0.92 20.768±10.37

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000521 CIL_000521_0001 CGP 20:33358839-33443892
CIL_0006PI CIL_0006PI_0001 CGP 20:33407955-33650036

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002027 IMP regulation of heart rate
GO:0003117 IEA regulation of vasoconstriction by circulating norepinephrine
GO:0003779 IEA actin binding
GO:0005515 IPI:IEA protein binding
GO:0005516 IEA calmodulin binding
GO:0005622 IDA intracellular
GO:0005737 IEA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0006936 TAS muscle contraction
GO:0007528 IEA neuromuscular junction development
GO:0016013 TAS syntrophin complex
GO:0016328 TAS lateral plasma membrane
GO:0017080 IMP sodium channel regulator activity
GO:0030054 IEA cell junction
GO:0030165 IEA PDZ domain binding
GO:0031594 IEA neuromuscular junction
GO:0042383 IEA sarcolemma
GO:0043234 IDA protein complex
GO:0044325 IPI ion channel binding
GO:0045211 IEA postsynaptic membrane
GO:0050998 IPI nitric-oxide synthase binding
GO:0051117 IPI ATPase binding
GO:0060307 IMP regulation of ventricular cardiac muscle cell membrane repolarization
GO:0086005 IMP ventricular cardiac muscle cell action potential
GO:1902083 IMP negative regulation of peptidyl-cysteine S-nitrosylation
GO:1902305 IMP regulation of sodium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000090781 SNTA1 syntrophin, alpha 1 protein_coding Danio_rerio
ENSMUSG00000027488 Snta1 syntrophin, acidic 1 protein_coding Mus_musculus

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