C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000101558 VAPA 9606 + 18:9914002-9960021 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000340541 VAPA-002 9914062-9954358 protein_coding
  ENST00000400000 VAPA-001 9914002-9960021 protein_coding
  ENST00000577539 VAPA-007 9947594-9951353 retained_intron
  ENST00000577901 VAPA-003 9914052-9936589 retained_intron
  ENST00000578314 VAPA-009 9914613-9925074 processed_transcript
  ENST00000583475 VAPA-004 9936727-9954477 retained_intron
  ENST00000583879 VAPA-006 9931777-9954226 retained_intron
  ENST00000584796 VAPA-008 9915770-9954143 processed_transcript
  ENST00000585042 VAPA-005 9914063-9936157 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000340541ENST00000400000ENST00000577539ENST00000577901ENST00000578314ENST00000583475ENST00000583879ENST00000584796
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000340541 40.199±0.00 29.360±0.00 N/A 47.580±0.00 35.485±0.00 45.469±0.00 26.488±0.00 14.981±0.00 25.151±0.00 21.758±0.00 26.410±0.00 11.800±2.17 9.306±0.63 20.416±5.03
ENST00000400000 7.804±0.00 8.382±0.00 1.314±0.00 10.469±3.85 5.578±2.72 5.696±3.88 3.690±1.91 2.960±1.11 2.987±0.75 3.485±0.90 3.856±2.42 9.169±6.15 3.461±0.27 5.839±3.01
ENST00000577539 N/A N/A 1.761±0.00 N/A 2.613±0.00 1.814±0.00 N/A 0.921±0.00 1.880±0.00 3.949±0.00 N/A 2.619±0.00 N/A N/A
ENST00000577901 N/A N/A N/A N/A N/A N/A 4.461±0.00 N/A N/A N/A 4.400±0.00 N/A N/A N/A
ENST00000578314 0.346±0.00 0.915±0.00 N/A 1.168±0.00 2.688±0.00 1.589±0.88 0.565±0.33 2.234±0.00 0.098±0.00 1.383±0.00 0.181±0.00 1.003±0.67 0.543±0.07 1.919±0.00
ENST00000583475 N/A N/A 4.527±0.00 17.663±0.00 11.939±1.96 13.034±3.51 10.911±1.90 N/A 8.562±0.00 14.248±0.00 9.199±3.61 14.786±4.53 7.268±0.00 20.482±0.00
ENST00000583879 N/A N/A N/A 17.408±0.00 9.600±0.00 6.355±0.00 14.891±0.00 8.093±0.00 6.561±0.00 N/A 18.378±0.00 23.997±11.05 25.471±0.00 16.771±0.00
ENST00000584796 N/A N/A 5.652±0.00 N/A N/A N/A 4.683±0.00 N/A N/A N/A 8.806±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004871 IMP signal transducer activity
GO:0005198 IEA structural molecule activity
GO:0005515 IPI protein binding
GO:0005783 IDA endoplasmic reticulum
GO:0005789 TAS:IEA endoplasmic reticulum membrane
GO:0005886 IDA plasma membrane
GO:0005923 IDA tight junction
GO:0006665 TAS sphingolipid metabolic process
GO:0007165 IMP signal transduction
GO:0008219 IMP cell death
GO:0015630 IEA microtubule cytoskeleton
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0030148 TAS sphingolipid biosynthetic process
GO:0031175 IMP neuron projection development
GO:0031982 IDA vesicle
GO:0043123 IMP positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0044281 TAS small molecule metabolic process
GO:0046982 IPI protein heterodimerization activity
GO:0048471 IDA perinuclear region of cytoplasm
GO:0061025 TAS membrane fusion
GO:0070972 IMP protein localization to endoplasmic reticulum

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004312 vapa VAMP (vesicle-associated membrane protein)-associated protein A protein_coding Danio_rerio
ENSDARG00000046048 vapal VAMP (vesicle-associated membrane protein)-associated protein A, like protein_coding Danio_rerio
ENSMUSG00000024091 Vapa vesicle-associated membrane protein, associated protein A protein_coding Mus_musculus

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