C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: X-linked inhibitor of apoptosis
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000101966 XIAP 9606 + X:123859724-123913979 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000355640 XIAP-009 123860272-123913965 protein_coding
  ENST00000371199 XIAP-002 123860027-123913979 protein_coding
  ENST00000422098 XIAP-007 123859724-123885711 protein_coding
  ENST00000430625 XIAP-005 123859878-123886130 protein_coding
  ENST00000434753 XIAP-201 123859812-123913976 protein_coding
  ENST00000468503 XIAP-010 123860454-123888683 processed_transcript
  ENST00000468691 XIAP-001 123859877-123907251 processed_transcript
  ENST00000481776 XIAP-003 123859764-123907020 processed_transcript
  ENST00000496602 XIAP-006 123912760-123913615 processed_transcript
  ENST00000497640 XIAP-004 123860195-123906998 processed_transcript
  ENST00000497906 XIAP-008 123859827-123900566 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000355640ENST00000371199ENST00000430625ENST00000434753
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000355640 N/A N/A 0.442±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 1.166±0.00 N/A 0.812±0.00
ENST00000371199 4.631±0.00 2.819±0.00 2.512±0.00 3.075±1.25 2.934±1.16 1.691±0.51 2.111±0.00 1.299±0.21 2.907±0.00 2.790±0.54 0.780±0.00 1.935±0.81 1.193±0.19 1.004±0.33
ENST00000430625 N/A N/A N/A N/A N/A N/A N/A 7.236±0.00 N/A N/A N/A N/A N/A N/A
ENST00000434753 0.790±0.00 N/A N/A 1.246±0.00 N/A 0.506±0.00 0.854±0.23 1.325±0.46 1.247±0.00 1.129±0.00 2.408±0.00 1.821±0.66 0.667±0.00 1.623±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000GB CIL_0000GB_0002 CGP X:123859724-124422664

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006915 TAS apoptotic process
GO:0006974 IEP cellular response to DNA damage stimulus
GO:0008270 IEA zinc ion binding
GO:0016055 IEA Wnt signaling pathway
GO:0016567 IDA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0030510 TAS regulation of BMP signaling pathway
GO:0031398 IDA positive regulation of protein ubiquitination
GO:0042127 TAS regulation of cell proliferation
GO:0043027 IDA cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0043066 IMP negative regulation of apoptotic process
GO:0043154 IDA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045088 TAS regulation of innate immune response
GO:0050727 TAS regulation of inflammatory response
GO:0055070 TAS copper ion homeostasis
GO:0070424 TAS regulation of nucleotide-binding oligomerization domain containing signaling pathway
GO:0090263 IMP positive regulation of canonical Wnt signaling pathway
GO:0097193 TAS intrinsic apoptotic signaling pathway
GO:1902530 IDA positive regulation of protein linear polyubiquitination

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016143 xiap X-linked inhibitor of apoptosis protein_coding Danio_rerio

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