C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: X-linked inhibitor of apoptosis
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000434753 XIAP-201 ENSG00000101966 9606 + X:123859812-123913976 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000434753
Transcript ID Adipose Brain Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000434753 0.790±0.00 1.246±0.00 0.506±0.00 0.854±0.23 1.325±0.46 1.247±0.00 1.129±0.00 2.408±0.00 1.821±0.66 0.667±0.00 1.623±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000GB CIL_0000GB_0002 CGP X:123859724-124422664

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006915 TAS apoptotic process
GO:0006974 IEP cellular response to DNA damage stimulus
GO:0008270 IEA zinc ion binding
GO:0016055 IEA Wnt signaling pathway
GO:0016567 IDA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0030510 TAS regulation of BMP signaling pathway
GO:0031398 IDA positive regulation of protein ubiquitination
GO:0042127 TAS regulation of cell proliferation
GO:0043027 IDA cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0043066 IMP negative regulation of apoptotic process
GO:0043154 IDA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045088 TAS regulation of innate immune response
GO:0050727 TAS regulation of inflammatory response
GO:0055070 TAS copper ion homeostasis
GO:0070424 TAS regulation of nucleotide-binding oligomerization domain containing signaling pathway
GO:0090263 IMP positive regulation of canonical Wnt signaling pathway
GO:0097193 TAS intrinsic apoptotic signaling pathway
GO:1902530 IDA positive regulation of protein linear polyubiquitination

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000055483 Xiap-001 protein_coding Mus_musculus 0 2966
ENSMUST00000026978 Xiap-002 protein_coding Mus_musculus 0 2964
ENSMUST00000115095 Xiap-004 protein_coding Mus_musculus 0 2964
ENSMUST00000115094 Xiap-003 protein_coding Mus_musculus 0 2964
ENSMUST00000145065 Xiap-005 processed_transcript Mus_musculus 0 1790
ENSMUST00000185660 RP24-269A16.5-001 processed_pseudogene Mus_musculus 0 1624
ENSMUST00000126375 Xiap-007 protein_coding Mus_musculus 0 267
ENSMUST00000187108 RP23-392H4.6-001 processed_pseudogene Mus_musculus 0 250
ENSMUST00000186774 RP23-315J23.2-001 processed_pseudogene Mus_musculus 0 248
ENSMUST00000048099 Tmem194-001 protein_coding Mus_musculus 0.0002 55

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