C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: FYVE, RhoGEF and PH domain containing 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000102302 FGD1 9606 - X:54445454-54496166 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000375135 FGD1-001 54445454-54496166 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000375135
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000375135 4.249±0.00 2.588±0.00 0.612±0.00 1.079±0.00 1.828±1.22 2.110±1.35 1.545±1.34 3.342±0.00 0.577±0.00 1.416±1.13 0.938±0.00 5.237±3.00 4.669±0.77 6.829±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001726 ISS ruffle
GO:0005085 IDA guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0005737 ISS cytoplasm
GO:0005794 ISS Golgi apparatus
GO:0005829 TAS cytosol
GO:0005856 IEA cytoskeleton
GO:0007010 ISS cytoskeleton organization
GO:0007165 TAS signal transduction
GO:0007264 TAS small GTPase mediated signal transduction
GO:0007275 TAS multicellular organismal development
GO:0008360 ISS regulation of cell shape
GO:0009887 TAS organ morphogenesis
GO:0030027 ISS lamellipodium
GO:0030036 IDA actin cytoskeleton organization
GO:0031267 IDA small GTPase binding
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0043065 TAS positive regulation of apoptotic process
GO:0043088 IDA regulation of Cdc42 GTPase activity
GO:0043547 IDA positive regulation of GTPase activity
GO:0046847 IDA filopodium assembly
GO:0046872 IEA metal ion binding
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0097190 TAS apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017473 fgd1 FYVE, RhoGEF and PH domain containing 1 protein_coding Danio_rerio
ENSDARG00000090746 fgd faciogenital dysplasia protein_coding Danio_rerio
ENSMUSG00000025265 Fgd1 FYVE, RhoGEF and PH domain containing 1 protein_coding Mus_musculus

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