C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: FYVE, RhoGEF and PH domain containing 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025265 Fgd1 10090 + X:151046150-151089521 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000026296 Fgd1-001 151047170-151089521 protein_coding
  ENSMUST00000112685 Fgd1-002 151046150-151089521 protein_coding
  ENSMUST00000124882 Fgd1-003 151067383-151069668 retained_intron
  ENSMUST00000125620 Fgd1-004 151086110-151087181 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000026296ENSMUST00000112685
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000026296 1.027±0.00 2.710±0.00 5.911±2.85 N/A 0.705±0.14 0.948±0.00 1.048±0.24 1.841±0.30 N/A 0.547±0.07 2.356±0.28 4.668±0.00 0.388±0.00
ENSMUST00000112685 1.769±0.86 1.306±0.00 N/A 0.892±0.21 0.770±0.06 1.049±0.16 1.277±0.20 0.575±0.00 0.778±0.08 0.675±0.00 3.100±0.18 9.834±8.14 0.382±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001726 IDA ruffle
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005794 IDA Golgi apparatus
GO:0005856 IEA cytoskeleton
GO:0007010 IDA cytoskeleton organization
GO:0008360 IDA regulation of cell shape
GO:0030027 IDA lamellipodium
GO:0030036 IEA actin cytoskeleton organization
GO:0031267 IEA small GTPase binding
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0043088 IEA regulation of Cdc42 GTPase activity
GO:0043547 IEA positive regulation of GTPase activity
GO:0046847 IEA filopodium assembly
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017473 fgd1 FYVE, RhoGEF and PH domain containing 1 protein_coding Danio_rerio
ENSDARG00000090746 fgd faciogenital dysplasia protein_coding Danio_rerio
ENSG00000102302 FGD1 FYVE, RhoGEF and PH domain containing 1 protein_coding Homo_sapiens

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