C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: heme oxygenase (decycling) 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000103415 HMOX2 9606 + 16:4474690-4510347 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000219700 HMOX2-004 4476379-4510346 protein_coding
  ENST00000398595 HMOX2-003 4495858-4509901 protein_coding
  ENST00000406590 HMOX2-201 4474703-4510346 protein_coding
  ENST00000414777 HMOX2-202 4495858-4510346 protein_coding
  ENST00000458134 HMOX2-002 4476340-4510295 protein_coding
  ENST00000570445 HMOX2-011 4476459-4508197 protein_coding
  ENST00000570622 HMOX2-012 4508059-4509779 protein_coding
  ENST00000570646 HMOX2-001 4475924-4510347 protein_coding
  ENST00000572812 HMOX2-008 4476412-4507838 protein_coding
  ENST00000574466 HMOX2-007 4476412-4507900 protein_coding
  ENST00000574594 HMOX2-013 4476442-4496762 processed_transcript
  ENST00000575051 HMOX2-005 4474690-4509430 protein_coding
  ENST00000575120 HMOX2-006 4476406-4509836 protein_coding
  ENST00000575129 HMOX2-010 4495858-4507904 protein_coding
  ENST00000576827 HMOX2-009 4476439-4507902 protein_coding
  ENST00000613539 HMOX2-203 4496146-4510346 protein_coding
  ENST00000619528 HMOX2-204 4476340-4510346 protein_coding
  ENST00000619913 HMOX2-205 4476340-4510346 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000219700ENST00000414777ENST00000458134ENST00000570445ENST00000570622ENST00000570646ENST00000575051ENST00000575120ENST00000575129ENST00000613539
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000219700 10.396±0.00 10.957±0.00 1.813±0.00 10.348±3.94 N/A 5.325±2.61 9.911±7.82 24.733±0.00 26.582±0.00 6.787±5.74 2.804±0.00 10.484±5.49 18.761±1.73 23.858±0.00
ENST00000414777 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 52.588±0.00
ENST00000458134 N/A 10.703±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000570445 N/A N/A 1.764±0.00 20.089±9.03 2.408±0.00 4.561±0.00 1.398±0.00 N/A 3.032±0.00 N/A 0.868±0.00 42.754±0.00 N/A 29.101±0.00
ENST00000570622 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 85.555±0.00 38.515±0.00 100.733±0.00
ENST00000570646 N/A N/A N/A 8.482±0.00 0.802±0.00 N/A 1.058±0.00 N/A N/A 0.752±0.00 N/A 11.433±2.92 10.883±0.00 12.967±0.00
ENST00000575051 N/A N/A N/A N/A N/A N/A 1.182±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000575120 33.167±0.00 33.106±0.00 N/A 25.870±16.21 14.387±11.89 11.043±8.94 23.829±22.16 20.995±18.03 54.718±0.00 35.123±0.00 4.512±3.07 18.112±3.17 23.825±2.64 71.503±0.00
ENST00000575129 N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.620±0.00 N/A N/A N/A N/A
ENST00000613539 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.346±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002BN CIL_0002BN_0001 CGP 16:4425805-4495763
CIL_00009E CIL_00009E_0001 CGP 16:4461680-4510347
CIL_0000TZ CIL_0000TZ_0001 CGP 16:4474690-4538828

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 IDA response to hypoxia
GO:0004392 IEA:IDA heme oxygenase (decyclizing) activity
GO:0005515 IPI protein binding
GO:0005789 TAS endoplasmic reticulum membrane
GO:0005886 IDA plasma membrane
GO:0006778 TAS porphyrin-containing compound metabolic process
GO:0006788 IEA heme oxidation
GO:0006879 TAS cellular iron ion homeostasis
GO:0006979 IEA response to oxidative stress
GO:0016020 IDA membrane
GO:0042167 TAS heme catabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding
GO:0055085 TAS transmembrane transport
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055101 hmox2a heme oxygenase (decycling) 2a protein_coding Danio_rerio
ENSDARG00000078452 hmox2b heme oxygenase (decycling) 2b protein_coding Danio_rerio
ENSMUSG00000004070 Hmox2 heme oxygenase (decycling) 2 protein_coding Mus_musculus

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