C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Fc fragment of IgG, receptor, transporter, alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000104870 FCGRT 9606 + 19:49506816-49526333 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000221466 FCGRT-001 49512279-49526333 protein_coding
  ENST00000426395 FCGRT-004 49513154-49526333 protein_coding
  ENST00000452439 FCGRT-006 49513395-49525164 retained_intron
  ENST00000593381 FCGRT-014 49513918-49524644 protein_coding
  ENST00000593431 FCGRT-019 49513398-49525012 retained_intron
  ENST00000594823 FCGRT-017 49513197-49524664 processed_transcript
  ENST00000595677 FCGRT-018 49513177-49521813 processed_transcript
  ENST00000595881 FCGRT-002 49513195-49526331 retained_intron
  ENST00000596147 FCGRT-008 49506816-49524780 retained_intron
  ENST00000596975 FCGRT-013 49513379-49526329 protein_coding
  ENST00000598076 FCGRT-016 49514058-49526333 protein_coding
  ENST00000598319 FCGRT-007 49513404-49525263 nonsense_mediated_decay
  ENST00000598491 FCGRT-009 49512375-49514309 protein_coding
  ENST00000598927 FCGRT-005 49512662-49526297 nonsense_mediated_decay
  ENST00000598936 FCGRT-011 49513390-49524568 retained_intron
  ENST00000599701 FCGRT-012 49512635-49514421 protein_coding
  ENST00000599988 FCGRT-020 49513255-49526333 protein_coding
  ENST00000600273 FCGRT-010 49513179-49514388 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000221466ENST00000426395ENST00000593381ENST00000593431ENST00000595677ENST00000595881ENST00000596975ENST00000598076ENST00000598319ENST00000598491ENST00000599988ENST00000600273
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000221466 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.012±0.00 N/A 43.420±0.00 N/A N/A
ENST00000426395 43.841±0.00 N/A N/A N/A 2.817±0.00 17.253±0.00 6.138±3.89 28.646±8.35 16.375±12.89 20.982±17.46 6.583±0.00 162.230±37.19 138.917±75.23 14.016±0.00
ENST00000593381 N/A N/A 3.394±0.00 N/A 5.738±0.00 5.314±0.00 N/A N/A N/A 4.047±0.00 N/A N/A N/A N/A
ENST00000593431 N/A N/A N/A 7.916±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000595677 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.100±0.00 N/A N/A N/A
ENST00000595881 N/A N/A N/A 1.145±0.00 1.026±0.00 1.271±0.00 0.535±0.00 N/A N/A N/A N/A N/A N/A 9.352±1.46
ENST00000596975 N/A N/A 6.052±0.00 3.319±0.52 3.812±0.00 22.968±15.12 10.257±8.44 25.405±0.00 N/A 21.466±18.47 5.820±0.00 37.044±0.00 92.917±18.61 13.686±1.62
ENST00000598076 92.111±0.00 72.596±0.00 N/A 9.820±0.00 61.845±0.00 51.209±0.00 30.102±0.00 44.632±0.00 74.514±0.00 84.614±0.00 17.733±0.00 N/A N/A 38.838±0.00
ENST00000598319 N/A N/A N/A N/A N/A 1.156±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000598491 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.416±0.00 N/A N/A
ENST00000599988 N/A N/A N/A 6.815±0.00 N/A N/A 16.420±0.00 22.855±0.00 70.343±0.00 N/A N/A 77.507±0.00 149.663±0.00 38.151±0.00
ENST00000600273 N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.887±0.00 N/A 34.688±0.00 89.829±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002416 NAS IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor
GO:0005515 IEA protein binding
GO:0005886 IEA plasma membrane
GO:0006955 IEA immune response
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019864 IDA IgG binding
GO:0019882 IEA antigen processing and presentation
GO:0030881 IEA beta-2-microglobulin binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000001470 mhc1zea major histocompatibility complex class I ZEA protein_coding Danio_rerio
ENSDARG00000036588 mhc1zba major histocompatibility complex class I ZBA protein_coding Danio_rerio
ENSDARG00000069471 mhc1zca major histocompatibility complex class I ZCA protein_coding Danio_rerio
ENSDARG00000074765 mhc1zaa major histocompatibility complex class I ZAA protein_coding Danio_rerio
ENSDARG00000076734 DARE-ZE*0601 Uncharacterized protein protein_coding Danio_rerio
ENSDARG00000088022 mhc1zfa major histocompatibility complex class I ZFA protein_coding Danio_rerio
ENSDARG00000092162 mhc1zaa major histocompatibility complex class I ZAA protein_coding Danio_rerio
ENSMUSG00000003420 Fcgrt Fc receptor, IgG, alpha chain transporter protein_coding Mus_musculus

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