C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cyclin E1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000105173 CCNE1 9606 + 19:29811898-29824308 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262643 CCNE1-001 29811898-29824308 protein_coding
  ENST00000357943 CCNE1-201 29812654-29824308 protein_coding
  ENST00000444983 CCNE1-002 29812654-29824212 protein_coding
  ENST00000574121 CCNE1-003 29821732-29824280 retained_intron
  ENST00000575243 CCNE1-004 29812004-29821768 protein_coding
  ENST00000576532 CCNE1-005 29817203-29824010 protein_coding
  ENST00000586912 CCNE1-006 29812725-29813331 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000262643ENST00000357943ENST00000444983ENST00000574121ENST00000575243ENST00000576532
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000262643 0.274±0.00 N/A 0.364±0.26 0.147±0.01 0.299±0.00 0.467±0.00 N/A N/A 0.314±0.00 N/A 8.821±6.43 26.825±6.00 2.629±1.17
ENST00000357943 0.284±0.00 N/A N/A N/A 0.768±0.00 N/A N/A N/A N/A N/A 7.905±8.18 4.133±0.00 1.455±0.00
ENST00000444983 0.239±0.00 0.283±0.00 0.508±0.03 0.334±0.07 N/A 0.440±0.17 0.452±0.00 0.039±0.00 N/A 0.592±0.00 23.142±7.70 24.217±0.00 2.735±0.91
ENST00000574121 N/A 0.561±0.00 N/A 0.142±0.00 N/A N/A N/A N/A N/A N/A 24.814±0.00 N/A 2.904±0.00
ENST00000575243 N/A N/A 0.728±0.00 0.482±0.19 N/A 0.656±0.00 0.241±0.00 0.137±0.09 0.137±0.00 N/A 10.124±0.00 N/A N/A
ENST00000576532 N/A N/A N/A N/A 0.396±0.00 0.084±0.00 N/A 0.114±0.00 0.183±0.00 0.089±0.00 N/A N/A 1.578±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008TZ CIL_0008TZ_0001 VISTA 19:29588658-30189738
CIL_000835 CIL_000835_0001 VISTA 19:29703707-30304596
CIL_000834 CIL_000834_0001 VISTA 19:29775043-30376109
CIL_00090S CIL_00090S_0001 VISTA 19:29783480-30384453

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000079 IEA regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000082 NAS G1/S transition of mitotic cell cycle
GO:0000083 TAS regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0000278 TAS mitotic cell cycle
GO:0000307 IEA cyclin-dependent protein kinase holoenzyme complex
GO:0003713 NAS transcription coactivator activity
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005829 TAS cytosol
GO:0006270 IEA DNA replication initiation
GO:0006468 IMP protein phosphorylation
GO:0016055 IEA Wnt signaling pathway
GO:0016301 IEA kinase activity
GO:0016538 IEA cyclin-dependent protein serine/threonine kinase regulator activity
GO:0019901 IEA protein kinase binding
GO:0030521 NAS androgen receptor signaling pathway
GO:0045859 IEA regulation of protein kinase activity
GO:0045893 NAS positive regulation of transcription, DNA-templated
GO:0050681 NAS androgen receptor binding
GO:0051301 IEA cell division
GO:0051726 IEA regulation of cell cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011133 ccne1 cyclin E1 protein_coding Danio_rerio
ENSMUSG00000002068 Ccne1 cyclin E1 protein_coding Mus_musculus

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