C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutaryl-CoA dehydrogenase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000105607 GCDH 9606 + 19:12891026-12914207 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000222214 GCDH-001 12891026-12899969 protein_coding
  ENST00000421816 GCDH-003 12891160-12897477 retained_intron
  ENST00000585420 GCDH-005 12891180-12899624 retained_intron
  ENST00000585760 GCDH-011 12891269-12892283 retained_intron
  ENST00000587072 GCDH-015 12891177-12893493 protein_coding
  ENST00000587832 GCDH-014 12891180-12893882 retained_intron
  ENST00000588242 GCDH-013 12899571-12900670 processed_transcript
  ENST00000588905 GCDH-010 12891168-12896015 protein_coding
  ENST00000589039 GCDH-008 12891160-12895995 protein_coding
  ENST00000590445 GCDH-009 12891164-12892129 nonsense_mediated_decay
  ENST00000590472 GCDH-012 12897303-12898383 protein_coding
  ENST00000590530 GCDH-004 12891166-12899969 nonsense_mediated_decay
  ENST00000590627 GCDH-006 12891180-12893834 retained_intron
  ENST00000591043 GCDH-007 12891269-12899678 retained_intron
  ENST00000591050 GCDH-016 12897380-12914207 protein_coding
  ENST00000591470 GCDH-002 12891160-12899946 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000222214ENST00000421816ENST00000585420ENST00000588905ENST00000590530ENST00000591043ENST00000591470
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000222214 N/A N/A N/A 0.710±0.00 N/A 2.067±0.00 1.682±0.00 10.121±0.00 N/A N/A 1.586±0.00 6.910±0.00 5.850±0.00 N/A
ENST00000421816 6.624±0.00 N/A N/A N/A N/A 2.404±0.00 N/A N/A 0.752±0.00 N/A N/A N/A N/A N/A
ENST00000585420 N/A 2.545±0.00 1.407±0.00 2.394±1.33 N/A N/A N/A 7.876±0.00 N/A 1.000±0.27 N/A N/A N/A N/A
ENST00000588905 N/A N/A 3.790±0.00 N/A N/A N/A N/A N/A 2.586±0.00 N/A N/A N/A N/A N/A
ENST00000590530 N/A 2.278±0.00 N/A N/A 5.058±0.00 N/A N/A N/A N/A 0.732±0.00 N/A 5.943±0.00 2.525±0.00 4.263±0.00
ENST00000591043 N/A N/A N/A 0.789±0.00 1.749±0.00 0.518±0.00 0.540±0.00 3.990±0.00 N/A 1.049±0.72 3.019±0.00 2.473±0.44 N/A N/A
ENST00000591470 4.484±0.00 5.562±0.00 2.001±0.00 5.800±0.00 4.805±3.24 3.609±0.00 8.593±0.00 9.541±1.58 17.143±16.46 1.687±0.00 4.295±2.35 6.305±3.68 5.560±2.99 3.951±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007VV CIL_0007VV_0001 VISTA 19:12752697-13356541
CIL_0007ZV CIL_0007ZV_0001 VISTA 19:12767682-13372012

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000062 IEA fatty-acyl-CoA binding
GO:0003995 IEA acyl-CoA dehydrogenase activity
GO:0004361 EXP glutaryl-CoA dehydrogenase activity
GO:0005739 IDA mitochondrion
GO:0005743 IEA mitochondrial inner membrane
GO:0005759 TAS mitochondrial matrix
GO:0006554 TAS lysine catabolic process
GO:0006568 IEA tryptophan metabolic process
GO:0006637 IEA acyl-CoA metabolic process
GO:0008152 IEA metabolic process
GO:0016627 IEA oxidoreductase activity, acting on the CH-CH group of donors
GO:0019395 IEA fatty acid oxidation
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046949 IEA fatty-acyl-CoA biosynthetic process
GO:0050660 IEA flavin adenine dinucleotide binding
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037057 gcdh glutaryl-Coenzyme A dehydrogenase protein_coding Danio_rerio
ENSDARG00000038361 gcdhl glutaryl-Coenzyme A dehydrogenase, like protein_coding Danio_rerio
ENSMUSG00000003809 Gcdh glutaryl-Coenzyme A dehydrogenase protein_coding Mus_musculus

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