C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: myotrophin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000105887 MTPN 9606 - 7:135926761-135977353 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000393085 MTPN-001 135926761-135977316 protein_coding
  ENST00000435723 MTPN-002 135929459-135977353 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000393085ENST00000435723
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000393085 35.966±0.00 20.054±0.00 5.864±0.00 41.790±8.36 20.426±6.09 20.190±9.37 12.406±8.06 15.979±8.03 11.386±1.53 27.637±11.92 9.461±5.46 17.035±4.89 20.255±4.48 26.541±7.50
ENST00000435723 N/A N/A 3.220±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00082N CIL_00082N_0001 VISTA 7:135472160-136074488
CIL_00024U CIL_00024U_0002 CGP 7:135728348-135977353
CIL_0007SR CIL_0007SR_0001 VISTA 7:135757880-136360968

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005634 ISS nucleus
GO:0005737 IEA cytoplasm
GO:0005829 ISS cytosol
GO:0006417 NAS regulation of translation
GO:0006584 IEA catecholamine metabolic process
GO:0008290 IDA F-actin capping protein complex
GO:0010557 ISS positive regulation of macromolecule biosynthetic process
GO:0010613 IMP positive regulation of cardiac muscle hypertrophy
GO:0016049 IDA cell growth
GO:0016202 NAS regulation of striated muscle tissue development
GO:0021707 IEA cerebellar granule cell differentiation
GO:0030182 NAS neuron differentiation
GO:0030307 ISS positive regulation of cell growth
GO:0030424 IEA axon
GO:0043403 IEA skeletal muscle tissue regeneration
GO:0051092 ISS positive regulation of NF-kappaB transcription factor activity
GO:0051146 IEA striated muscle cell differentiation
GO:0051247 ISS positive regulation of protein metabolic process
GO:0070062 IDA extracellular vesicular exosome
GO:2000812 IDA regulation of barbed-end actin filament capping

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055562 mtpn myotrophin protein_coding Danio_rerio
ENSMUSG00000029840 Mtpn myotrophin protein_coding Mus_musculus

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