C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: heat shock 27kDa protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000106211 HSPB1 9606 + 7:76302544-76304295 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000248553 HSPB1-001 76302544-76304295 protein_coding
  ENST00000429938 HSPB1-003 76303577-76304295 protein_coding
  ENST00000447574 HSPB1-002 76302688-76304260 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000248553ENST00000429938ENST00000447574
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000248553 453.265±0.00 572.994±0.00 13.575±0.00 36.855±31.98 207.534±187.70 848.010±832.44 189.680±175.95 305.291±292.47 54.804±14.85 327.424±317.31 743.333±587.85 536.377±469.32 695.296±296.76 281.377±245.59
ENST00000429938 N/A N/A N/A 1.658±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000447574 N/A N/A 2.458±0.00 0.426±0.00 3.286±0.00 1.078±0.00 1.832±0.00 N/A 2.490±0.00 7.681±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006NG CIL_0006NG_0001 CGP 7:76201900-76304295
CIL_0006NF CIL_0006NF_0001 CGP 7:76302544-76359031

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000502 ISS proteasome complex
GO:0001895 IEP retina homeostasis
GO:0005080 ISS protein kinase C binding
GO:0005515 IPI protein binding
GO:0005615 IDA extracellular space
GO:0005622 IEA intracellular
GO:0005634 IDA nucleus
GO:0005737 TAS cytoplasm
GO:0005829 TAS cytosol
GO:0005856 TAS cytoskeleton
GO:0005886 IEA plasma membrane
GO:0005925 IDA focal adhesion
GO:0006446 TAS regulation of translational initiation
GO:0006469 ISS negative regulation of protein kinase activity
GO:0006928 TAS cellular component movement
GO:0006986 NAS response to unfolded protein
GO:0008219 IEA cell death
GO:0008426 ISS protein kinase C inhibitor activity
GO:0009615 IEP response to virus
GO:0010467 TAS gene expression
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0019901 IPI protein kinase binding
GO:0030018 IEA Z disc
GO:0032731 ISS positive regulation of interleukin-1 beta production
GO:0035556 IMP intracellular signal transduction
GO:0035924 IMP cellular response to vascular endothelial growth factor stimulus
GO:0038033 IMP positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway
GO:0042535 ISS positive regulation of tumor necrosis factor biosynthetic process
GO:0042802 IPI identical protein binding
GO:0043066 TAS negative regulation of apoptotic process
GO:0043122 ISS regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043130 ISS ubiquitin binding
GO:0043292 IEA contractile fiber
GO:0043536 IMP positive regulation of blood vessel endothelial cell migration
GO:0044822 IDA poly(A) RNA binding
GO:0045766 IMP positive regulation of angiogenesis
GO:0070062 IDA extracellular vesicular exosome
GO:0070527 IMP platelet aggregation
GO:0071901 IEA negative regulation of protein serine/threonine kinase activity
GO:1902176 ISS negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
GO:2001028 IMP positive regulation of endothelial cell chemotaxis
GO:2001234 IEA negative regulation of apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041065 hspb1 heat shock protein, alpha-crystallin-related, 1 protein_coding Danio_rerio
ENSMUSG00000004951 Hspb1 heat shock protein 1 protein_coding Mus_musculus

Loading