C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: heat shock protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000004951 Hspb1 10090 + 5:135887919-135889563 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000005077 Hspb1-001 135887919-135889563 protein_coding
  ENSMUST00000111155 Hspb1-002 135888018-135889561 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000005077ENSMUST00000111155
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000005077 86.005±9.84 78.305±35.92 375.982±29.35 5.660±2.52 69.635±27.25 118.314±3.11 168.938±42.07 23.128±1.74 2.959±1.73 123.031±24.11 95.594±12.38 74.679±10.21 499.418±167.38 16.741±6.58
ENSMUST00000111155 N/A N/A N/A N/A N/A N/A N/A N/A N/A 24.776±1.33 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006NG CIL_0006NG_0002 CGP 5:135806890-135889563
CIL_0006NF CIL_0006NF_0002 CGP 5:135887919-135934616

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000502 ISS proteasome complex
GO:0001895 IEA retina homeostasis
GO:0005080 IDA protein kinase C binding
GO:0005515 IEA protein binding
GO:0005615 IEA extracellular space
GO:0005622 IDA intracellular
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0005886 IDA plasma membrane
GO:0005925 IEA focal adhesion
GO:0006469 IDA negative regulation of protein kinase activity
GO:0006986 NAS response to unfolded protein
GO:0008426 IDA protein kinase C inhibitor activity
GO:0009615 ISS response to virus
GO:0019901 IEA protein kinase binding
GO:0030018 IDA Z disc
GO:0032731 IDA positive regulation of interleukin-1 beta production
GO:0035556 IEA intracellular signal transduction
GO:0035924 IEA cellular response to vascular endothelial growth factor stimulus
GO:0038033 IEA positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway
GO:0042535 IDA positive regulation of tumor necrosis factor biosynthetic process
GO:0042802 IEA identical protein binding
GO:0043122 IDA regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043130 ISS ubiquitin binding
GO:0043292 IDA contractile fiber
GO:0043536 IEA positive regulation of blood vessel endothelial cell migration
GO:0044822 IEA poly(A) RNA binding
GO:0045766 IEA positive regulation of angiogenesis
GO:0070062 IEA extracellular vesicular exosome
GO:0070527 IEA platelet aggregation
GO:0071901 IDA negative regulation of protein serine/threonine kinase activity
GO:1902176 IDA negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
GO:2001028 IEA positive regulation of endothelial cell chemotaxis
GO:2001234 IDA negative regulation of apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041065 hspb1 heat shock protein, alpha-crystallin-related, 1 protein_coding Danio_rerio
ENSG00000106211 HSPB1 heat shock 27kDa protein 1 protein_coding Homo_sapiens

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