C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: eukaryotic translation initiation factor 3, subunit B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000106263 EIF3B 9606 + 7:2354086-2380745 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000360876 EIF3B-002 2354866-2380743 protein_coding
  ENST00000397011 EIF3B-001 2354882-2380745 protein_coding
  ENST00000413917 EIF3B-003 2354867-2364396 protein_coding
  ENST00000431643 EIF3B-008 2354086-2366435 protein_coding
  ENST00000463026 EIF3B-010 2364324-2366743 retained_intron
  ENST00000463229 EIF3B-009 2363021-2367024 retained_intron
  ENST00000465670 EIF3B-007 2377824-2380740 retained_intron
  ENST00000466199 EIF3B-012 2366530-2372190 retained_intron
  ENST00000468250 EIF3B-011 2364324-2367119 retained_intron
  ENST00000468611 EIF3B-006 2375975-2380740 retained_intron
  ENST00000475415 EIF3B-005 2373118-2380740 retained_intron
  ENST00000494658 EIF3B-013 2378687-2379841 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000360876ENST00000397011ENST00000431643ENST00000494658
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000360876 N/A 10.827±0.00 N/A 16.695±0.00 29.332±0.00 9.078±3.06 15.724±0.00 11.674±8.04 9.432±4.56 14.057±0.00 17.711±15.41 25.429±16.62 33.754±2.07 29.053±3.49
ENST00000397011 19.195±0.00 15.358±0.00 3.933±0.00 7.744±3.36 11.070±3.56 26.210±0.00 4.801±2.58 10.551±4.07 8.173±6.52 8.615±1.25 33.958±30.38 36.168±21.20 32.744±17.57 46.071±22.60
ENST00000431643 N/A N/A 1.871±0.00 N/A N/A N/A N/A N/A 3.656±0.00 N/A N/A N/A N/A N/A
ENST00000494658 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 117.520±0.00 64.294±0.00 76.040±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000ZO CIL_0000ZO_0001 CGP 7:2242222-2354318
CIL_0000ZL CIL_0000ZL_0001 CGP 7:2251770-2380745
CIL_0007RS CIL_0007RS_0001 VISTA 7:2311652-2915186
CIL_00027M CIL_00027M_0002 CGP 7:2354086-2434607

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0001731 IEA formation of translation preinitiation complex
GO:0003676 IEA nucleic acid binding
GO:0003723 IEA RNA binding
GO:0003743 IDA:IEA translation initiation factor activity
GO:0005515 IPI protein binding
GO:0005829 TAS cytosol
GO:0005852 IDA:IEA eukaryotic translation initiation factor 3 complex
GO:0006412 TAS translation
GO:0006413 IC:IEA translational initiation
GO:0006446 IDA regulation of translational initiation
GO:0010467 TAS gene expression
GO:0016282 IEA eukaryotic 43S preinitiation complex
GO:0031369 IEA translation initiation factor binding
GO:0032947 TAS protein complex scaffold
GO:0033290 IEA eukaryotic 48S preinitiation complex
GO:0044267 TAS cellular protein metabolic process
GO:0070062 IDA extracellular vesicular exosome
GO:0071541 IEA eukaryotic translation initiation factor 3 complex, eIF3m

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059654 eif3ba eukaryotic translation initiation factor 3, subunit Ba protein_coding Danio_rerio
ENSDARG00000074213 eif3bb eukaryotic translation initiation factor 3, subunit Bb protein_coding Danio_rerio
ENSMUSG00000056076 Eif3b eukaryotic translation initiation factor 3, subunit B protein_coding Mus_musculus

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