C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein kinase, AMP-activated, gamma 2 non-catalytic subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000106617 PRKAG2 9606 - 7:151556111-151877125 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000287878 PRKAG2-001 151556111-151877125 protein_coding
  ENST00000392801 PRKAG2-003 151556941-151814840 protein_coding
  ENST00000418337 PRKAG2-002 151556124-151632353 protein_coding
  ENST00000461529 PRKAG2-008 151675548-151790632 processed_transcript
  ENST00000474383 PRKAG2-007 151837268-151876788 processed_transcript
  ENST00000476632 PRKAG2-010 151568737-151633165 protein_coding
  ENST00000478989 PRKAG2-015 151564195-151574951 nonsense_mediated_decay
  ENST00000479461 PRKAG2-017 151556993-151564313 retained_intron
  ENST00000481434 PRKAG2-005 151674939-151877125 retained_intron
  ENST00000483775 PRKAG2-013 151576183-151632227 retained_intron
  ENST00000485183 PRKAG2-016 151560375-151564314 retained_intron
  ENST00000487375 PRKAG2-009 151675419-151736178 processed_transcript
  ENST00000488258 PRKAG2-006 151568694-151876848 nonsense_mediated_decay
  ENST00000491938 PRKAG2-014 151572408-151632168 retained_intron
  ENST00000492843 PRKAG2-004 151556161-151736314 protein_coding
  ENST00000493872 PRKAG2-012 151570190-151632177 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000287878ENST00000418337ENST00000476632ENST00000479461ENST00000481434ENST00000488258ENST00000491938ENST00000492843
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000287878 6.444±0.00 2.281±0.00 N/A 1.729±0.76 1.899±0.83 1.882±0.00 N/A 1.704±0.00 3.178±0.00 1.212±0.05 0.487±0.00 1.725±0.70 N/A 1.350±0.21
ENST00000418337 N/A 7.121±0.00 N/A 5.835±3.91 1.981±0.75 7.392±0.00 21.104±0.00 9.030±0.00 2.679±0.00 3.358±0.00 0.773±0.00 2.457±1.12 10.905±5.39 5.051±3.58
ENST00000476632 N/A N/A N/A N/A N/A 1.331±0.00 N/A N/A N/A 1.336±0.00 N/A N/A N/A N/A
ENST00000479461 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.311±0.00 N/A N/A N/A
ENST00000481434 N/A N/A 1.150±0.00 N/A N/A N/A N/A 2.740±0.00 N/A N/A N/A N/A N/A N/A
ENST00000488258 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.121±0.00 N/A N/A N/A N/A
ENST00000491938 N/A N/A N/A N/A N/A N/A N/A N/A 7.971±0.00 N/A 1.686±0.00 N/A N/A N/A
ENST00000492843 N/A N/A 0.496±0.00 0.760±0.00 N/A 0.613±0.00 7.719±4.75 N/A N/A N/A N/A 1.203±0.00 3.443±0.00 3.711±1.70

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007RX CIL_0007RX_0001 VISTA 7:151109813-151711422
CIL_0007T7 CIL_0007T7_0001 VISTA 7:151442692-152046426
CIL_0007T1 CIL_0007T1_0001 VISTA 7:151456863-152060019
CIL_000458 CIL_000458_0001 CGP 7:151466012-151877125

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004679 IEA AMP-activated protein kinase activity
GO:0004862 IDA cAMP-dependent protein kinase inhibitor activity
GO:0005524 IDA ATP binding
GO:0005615 IDA extracellular space
GO:0005654 TAS nucleoplasm
GO:0005829 TAS cytosol
GO:0005977 IMP glycogen metabolic process
GO:0006110 IMP regulation of glycolytic process
GO:0006112 TAS energy reserve metabolic process
GO:0006468 IEA protein phosphorylation
GO:0006469 IDA negative regulation of protein kinase activity
GO:0006633 IEA fatty acid biosynthetic process
GO:0006754 TAS ATP biosynthetic process
GO:0006853 TAS carnitine shuttle
GO:0007050 TAS cell cycle arrest
GO:0008286 TAS insulin receptor signaling pathway
GO:0008603 IMP cAMP-dependent protein kinase regulator activity
GO:0008607 IMP phosphorylase kinase regulator activity
GO:0010800 IMP positive regulation of peptidyl-threonine phosphorylation
GO:0016126 TAS sterol biosynthetic process
GO:0016208 IEA AMP binding
GO:0019217 IMP regulation of fatty acid metabolic process
GO:0019901 IDA protein kinase binding
GO:0030295 IMP protein kinase activator activity
GO:0030554 IEA adenyl nucleotide binding
GO:0031588 IDA AMP-activated protein kinase complex
GO:0035556 IMP intracellular signal transduction
GO:0042304 TAS regulation of fatty acid biosynthetic process
GO:0043531 IDA ADP binding
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045860 IMP positive regulation of protein kinase activity
GO:0046320 TAS regulation of fatty acid oxidation
GO:0046324 TAS regulation of glucose import
GO:0050790 IEA regulation of catalytic activity
GO:0061024 TAS membrane organization
GO:0071901 IDA negative regulation of protein serine/threonine kinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000012625 prkag2a protein kinase, AMP-activated, gamma 2 non-catalytic subunit a protein_coding Danio_rerio
ENSMUSG00000028944 Prkag2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit protein_coding Mus_musculus

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