C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein kinase, AMP-activated, gamma 2 non-catalytic subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028944 Prkag2 10090 - 5:24862744-25100642 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030784 Prkag2-001 24862744-25100642 protein_coding
  ENSMUST00000076306 Prkag2-002 24862748-24995753 protein_coding
  ENSMUST00000114975 Prkag2-003 24862748-24908469 protein_coding
  ENSMUST00000123749 Prkag2-006 24889161-24908977 protein_coding
  ENSMUST00000129022 Prkag2-009 24874874-24889152 retained_intron
  ENSMUST00000131486 Prkag2-008 24871537-24902315 protein_coding
  ENSMUST00000135525 Prkag2-010 24863776-24871753 retained_intron
  ENSMUST00000139698 Prkag2-005 24875400-24908452 retained_intron
  ENSMUST00000148531 Prkag2-007 24906231-24908450 processed_transcript
  ENSMUST00000150135 Prkag2-004 24869255-24908509 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000030784ENSMUST00000076306ENSMUST00000114975ENSMUST00000135525ENSMUST00000150135
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000030784 13.540±1.50 6.543±2.17 8.523±0.21 4.473±0.00 6.323±1.85 4.751±0.51 4.222±1.11 12.782±1.93 4.413±2.74 5.631±0.66 0.738±0.22 5.540±1.62 1.861±0.74 39.491±16.88
ENSMUST00000076306 N/A N/A 7.814±0.67 N/A N/A 2.686±0.33 3.926±0.81 N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000114975 N/A N/A 23.730±9.61 23.300±0.15 N/A N/A N/A N/A 1.709±0.39 N/A 3.956±0.90 7.826±0.00 4.092±1.27 N/A
ENSMUST00000135525 N/A N/A N/A 93.203±0.00 12.024±0.00 12.813±0.00 N/A N/A N/A N/A N/A 97.645±0.00 41.414±10.80 301.336±0.00
ENSMUST00000150135 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.717±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007RX CIL_0007RX_0002 VISTA 5:24430554-25031843
CIL_0007T7 CIL_0007T7_0002 VISTA 5:24699254-25303507
CIL_0007T1 CIL_0007T1_0002 VISTA 5:24708595-25311977
CIL_000458 CIL_000458_0002 CGP 5:24802823-25100642

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004679 TAS AMP-activated protein kinase activity
GO:0004862 IEA cAMP-dependent protein kinase inhibitor activity
GO:0005524 IEA ATP binding
GO:0005615 IEA extracellular space
GO:0005829 TAS cytosol
GO:0005977 IEA glycogen metabolic process
GO:0006110 IEA regulation of glycolytic process
GO:0006468 TAS protein phosphorylation
GO:0006469 IEA negative regulation of protein kinase activity
GO:0006633 IEA fatty acid biosynthetic process
GO:0008603 IEA cAMP-dependent protein kinase regulator activity
GO:0008607 IEA phosphorylase kinase regulator activity
GO:0010800 IEA positive regulation of peptidyl-threonine phosphorylation
GO:0016208 IEA AMP binding
GO:0019217 IEA regulation of fatty acid metabolic process
GO:0019901 IEA protein kinase binding
GO:0030295 IEA protein kinase activator activity
GO:0030554 IEA adenyl nucleotide binding
GO:0031588 IEA AMP-activated protein kinase complex
GO:0035556 IEA intracellular signal transduction
GO:0043531 IEA ADP binding
GO:0045860 IEA positive regulation of protein kinase activity
GO:0050790 IEA regulation of catalytic activity
GO:0071901 IEA negative regulation of protein serine/threonine kinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000012625 prkag2a protein kinase, AMP-activated, gamma 2 non-catalytic subunit a protein_coding Danio_rerio
ENSG00000106617 PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit protein_coding Homo_sapiens

Loading