C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: protein kinase, AMP-activated, gamma 2 non-catalytic subunit
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000418337 PRKAG2-002 ENSG00000106617 9606 - 7:151556124-151632353 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000418337
Transcript ID Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000418337 7.121±0.00 5.835±3.91 1.981±0.75 7.392±0.00 21.104±0.00 9.030±0.00 2.679±0.00 3.358±0.00 0.773±0.00 2.457±1.12 10.905±5.39 5.051±3.58

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007RX CIL_0007RX_0001 VISTA 7:151109813-151711422
CIL_0007T7 CIL_0007T7_0001 VISTA 7:151442692-152046426
CIL_0007T1 CIL_0007T1_0001 VISTA 7:151456863-152060019
CIL_000458 CIL_000458_0001 CGP 7:151466012-151877125

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004862 IDA cAMP-dependent protein kinase inhibitor activity
GO:0005524 IDA ATP binding
GO:0005615 IDA extracellular space
GO:0005654 TAS nucleoplasm
GO:0005829 TAS cytosol
GO:0005977 IMP glycogen metabolic process
GO:0006110 IMP regulation of glycolytic process
GO:0006112 TAS energy reserve metabolic process
GO:0006469 IDA negative regulation of protein kinase activity
GO:0006633 IEA fatty acid biosynthetic process
GO:0006754 TAS ATP biosynthetic process
GO:0006853 TAS carnitine shuttle
GO:0007050 TAS cell cycle arrest
GO:0008286 TAS insulin receptor signaling pathway
GO:0008603 IMP cAMP-dependent protein kinase regulator activity
GO:0008607 IMP phosphorylase kinase regulator activity
GO:0010800 IMP positive regulation of peptidyl-threonine phosphorylation
GO:0016126 TAS sterol biosynthetic process
GO:0019217 IMP regulation of fatty acid metabolic process
GO:0019901 IDA protein kinase binding
GO:0030295 IMP protein kinase activator activity
GO:0031588 IDA AMP-activated protein kinase complex
GO:0035556 IMP intracellular signal transduction
GO:0042304 TAS regulation of fatty acid biosynthetic process
GO:0043531 IDA ADP binding
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045860 IMP positive regulation of protein kinase activity
GO:0046320 TAS regulation of fatty acid oxidation
GO:0046324 TAS regulation of glucose import
GO:0061024 TAS membrane organization
GO:0071901 IDA negative regulation of protein serine/threonine kinase activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000114975 Prkag2-003 protein_coding Mus_musculus 0 1862
ENSMUST00000076306 Prkag2-002 protein_coding Mus_musculus 0 1825
ENSMUST00000030784 Prkag2-001 protein_coding Mus_musculus 0 1812
ENSMUST00000150135 Prkag2-004 protein_coding Mus_musculus 0 1160
ENSMUST00000131486 Prkag2-008 protein_coding Mus_musculus 0 870
ENSMUST00000135525 Prkag2-010 retained_intron Mus_musculus 0 780
ENSDART00000129174 prkag2a-201 protein_coding Danio_rerio 0 699
ENSDART00000148618 prkag2a-001 protein_coding Danio_rerio 0 699
ENSMUST00000139698 Prkag2-005 retained_intron Mus_musculus 0 540
ENSMUST00000129022 Prkag2-009 retained_intron Mus_musculus 0 407
ENSMUST00000148531 Prkag2-007 processed_transcript Mus_musculus 9e-37 159
ENSMUST00000123749 Prkag2-006 protein_coding Mus_musculus 5e-29 134

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