C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: GATA binding protein 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000107485 GATA3 9606 + 10:8053604-8075198 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000346208 GATA3-002 8054806-8074890 protein_coding
  ENST00000379328 GATA3-001 8054693-8075198 protein_coding
  ENST00000461472 GATA3-004 8058399-8074064 processed_transcript
  ENST00000481743 GATA3-003 8053604-8055553 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000346208ENST00000379328ENST00000461472ENST00000481743
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000346208 1.629±0.00 2.350±0.00 0.697±0.00 0.048±0.00 6.669±6.09 0.105±0.09 0.100±0.06 13.972±0.00 0.745±0.29 2.929±0.00 0.230±0.12 0.142±0.10 26.758±8.38 1.207±1.00
ENST00000379328 0.805±0.00 0.792±0.00 N/A 0.035±0.00 3.993±0.00 N/A 0.297±0.00 8.121±0.00 N/A 0.796±0.00 0.115±0.00 0.128±0.08 20.925±5.73 0.346±0.00
ENST00000461472 N/A N/A N/A 0.045±0.00 N/A N/A 0.396±0.00 N/A N/A 2.550±0.00 0.468±0.00 0.101±0.00 N/A N/A
ENST00000481743 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.256±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007J5 CIL_0007J5_0001 UCNEbase 10:7952337-8505078

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000790 IDA nuclear chromatin
GO:0000902 IEA cell morphogenesis
GO:0000976 IDA transcription regulatory region sequence-specific DNA binding
GO:0000977 IEA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000979 IEA RNA polymerase II core promoter sequence-specific DNA binding
GO:0000987 IDA core promoter proximal region sequence-specific DNA binding
GO:0001046 IDA core promoter sequence-specific DNA binding
GO:0001071 IDA nucleic acid binding transcription factor activity
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001078 IMP RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001158 IEA enhancer sequence-specific DNA binding
GO:0001701 IEA in utero embryonic development
GO:0001709 ISS cell fate determination
GO:0001764 IEA neuron migration
GO:0001775 IEA cell activation
GO:0001806 IEA type IV hypersensitivity
GO:0001819 IEA positive regulation of cytokine production
GO:0001822 IMP kidney development
GO:0001823 ISS mesonephros development
GO:0002088 IEA lens development in camera-type eye
GO:0002572 IEA pro-T cell differentiation
GO:0003180 ISS aortic valve morphogenesis
GO:0003215 ISS cardiac right ventricle morphogenesis
GO:0003281 ISS ventricular septum development
GO:0003677 TAS DNA binding
GO:0003700 TAS:IEA sequence-specific DNA binding transcription factor activity
GO:0003713 IDA transcription coactivator activity
GO:0005134 IEA interleukin-2 receptor binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005730 IDA nucleolus
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006952 TAS defense response
GO:0006959 IEA humoral immune response
GO:0007165 ISS signal transduction
GO:0007399 IEA nervous system development
GO:0007411 IEA axon guidance
GO:0007596 TAS blood coagulation
GO:0008134 IPI transcription factor binding
GO:0008270 IEA zinc ion binding
GO:0008285 ISS negative regulation of cell proliferation
GO:0008584 ISS male gonad development
GO:0009615 IEP response to virus
GO:0009653 TAS anatomical structure morphogenesis
GO:0009791 IEA post-embryonic development
GO:0009967 IMP positive regulation of signal transduction
GO:0010332 IEA response to gamma radiation
GO:0010595 IMP positive regulation of endothelial cell migration
GO:0010629 IEA negative regulation of gene expression
GO:0010975 IEA regulation of neuron projection development
GO:0014065 ISS phosphatidylinositol 3-kinase signaling
GO:0030182 IEA neuron differentiation
GO:0030217 IEA T cell differentiation
GO:0030218 IEA erythrocyte differentiation
GO:0031929 ISS TOR signaling
GO:0032689 IEA negative regulation of interferon-gamma production
GO:0032703 IEA negative regulation of interleukin-2 production
GO:0032736 IEA positive regulation of interleukin-13 production
GO:0032753 ISS positive regulation of interleukin-4 production
GO:0032754 IEA positive regulation of interleukin-5 production
GO:0033077 IEA T cell differentiation in thymus
GO:0033600 IDA negative regulation of mammary gland epithelial cell proliferation
GO:0035162 IEA embryonic hemopoiesis
GO:0035457 IEP cellular response to interferon-alpha
GO:0035799 IEA ureter maturation
GO:0035898 IEA parathyroid hormone secretion
GO:0042035 ISS regulation of cytokine biosynthetic process
GO:0042421 ISS norepinephrine biosynthetic process
GO:0042472 IEA inner ear morphogenesis
GO:0042493 IEA response to drug
GO:0043370 IEA regulation of CD4-positive, alpha-beta T cell differentiation
GO:0043523 IEA regulation of neuron apoptotic process
GO:0043565 IEA sequence-specific DNA binding
GO:0043583 IMP ear development
GO:0043627 IEP response to estrogen
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045061 IEA thymic T cell selection
GO:0045064 IEA T-helper 2 cell differentiation
GO:0045087 IEA innate immune response
GO:0045471 IEA response to ethanol
GO:0045582 ISS positive regulation of T cell differentiation
GO:0045597 IEA positive regulation of cell differentiation
GO:0045599 IMP negative regulation of fat cell differentiation
GO:0045786 IMP negative regulation of cell cycle
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0046983 IEA protein dimerization activity
GO:0048469 IEA cell maturation
GO:0048485 ISS sympathetic nervous system development
GO:0048538 IEA thymus development
GO:0048568 IEA embryonic organ development
GO:0048589 IEA developmental growth
GO:0048646 ISS anatomical structure formation involved in morphogenesis
GO:0048872 IEA homeostasis of number of cells
GO:0050728 IMP negative regulation of inflammatory response
GO:0050852 ISS T cell receptor signaling pathway
GO:0051569 IEA regulation of histone H3-K4 methylation
GO:0051897 IMP positive regulation of protein kinase B signaling
GO:0060017 IEA parathyroid gland development
GO:0060037 ISS pharyngeal system development
GO:0060065 ISS uterus development
GO:0060231 IDA mesenchymal to epithelial transition
GO:0060374 IEA mast cell differentiation
GO:0060676 ISS ureteric bud formation
GO:0061085 IEA regulation of histone H3-K27 methylation
GO:0061290 ISS canonical Wnt signaling pathway involved in metanephric kidney development
GO:0070888 IDA E-box binding
GO:0071345 IEA cellular response to cytokine stimulus
GO:0071353 IEP cellular response to interleukin-4
GO:0071356 IEP cellular response to tumor necrosis factor
GO:0071599 IEA otic vesicle development
GO:0071773 IEA cellular response to BMP stimulus
GO:0071837 IPI HMG box domain binding
GO:0072001 IEA renal system development
GO:0072107 ISS positive regulation of ureteric bud formation
GO:0072178 ISS nephric duct morphogenesis
GO:0072179 ISS nephric duct formation
GO:0072182 ISS regulation of nephron tubule epithelial cell differentiation
GO:0072602 IEA interleukin-4 secretion
GO:0072643 IEA interferon-gamma secretion
GO:0072676 IDA lymphocyte migration
GO:2000114 IEA regulation of establishment of cell polarity
GO:2000146 IMP negative regulation of cell motility
GO:2000352 IMP negative regulation of endothelial cell apoptotic process
GO:2000607 ISS negative regulation of cell proliferation involved in mesonephros development
GO:2000611 IMP positive regulation of thyroid hormone generation
GO:2000664 IDA positive regulation of interleukin-5 secretion
GO:2000667 IMP positive regulation of interleukin-13 secretion
GO:2000679 IMP positive regulation of transcription regulatory region DNA binding
GO:2000683 IMP regulation of cellular response to X-ray
GO:2000703 ISS negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation
GO:2000734 ISS negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016526 gata3 GATA-binding protein 3 protein_coding Danio_rerio
ENSMUSG00000015619 Gata3 GATA binding protein 3 protein_coding Mus_musculus

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