C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000107679 PLEKHA1 9606 + 10:122374696-122442602 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000368988 PLEKHA1-201 122393105-122432354 protein_coding
  ENST00000368989 PLEKHA1-001 122374760-122432345 protein_coding
  ENST00000368990 PLEKHA1-002 122374696-122442602 protein_coding
  ENST00000392799 PLEKHA1-004 122386609-122430479 protein_coding
  ENST00000433307 PLEKHA1-202 122393128-122432354 protein_coding
  ENST00000463663 PLEKHA1-009 122374834-122412976 protein_coding
  ENST00000481451 PLEKHA1-006 122411771-122425731 retained_intron
  ENST00000494222 PLEKHA1-007 122374696-122416006 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000368988ENST00000368989ENST00000368990ENST00000392799ENST00000433307ENST00000481451
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000368988 1.398±0.00 N/A N/A 4.360±0.00 N/A N/A N/A 3.439±0.00 N/A N/A N/A N/A N/A 6.612±2.42
ENST00000368989 5.929±0.00 2.955±0.00 N/A 8.541±3.72 7.216±0.00 7.030±0.00 4.825±1.97 16.380±0.00 2.948±1.80 15.125±0.00 6.267±5.56 4.039±0.77 4.514±1.59 3.945±0.00
ENST00000368990 N/A N/A N/A 0.417±0.00 N/A N/A N/A 0.322±0.00 N/A N/A N/A N/A N/A N/A
ENST00000392799 N/A N/A 1.818±0.00 N/A N/A 2.705±0.00 N/A N/A N/A N/A 0.719±0.00 N/A N/A N/A
ENST00000433307 N/A 1.787±0.00 2.415±0.00 4.303±0.75 2.715±0.00 3.039±0.00 N/A 4.055±0.17 2.493±0.79 3.465±0.00 N/A 8.913±8.02 5.290±0.90 3.082±1.04
ENST00000481451 N/A 0.451±0.00 0.567±0.00 0.529±0.00 0.788±0.00 N/A 0.663±0.00 0.692±0.00 0.662±0.00 N/A 0.128±0.00 1.060±0.76 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001BB CIL_0001BB_0001 CGP 10:122271306-122442602

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001553 IEA luteinization
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0007283 IEA spermatogenesis
GO:0008209 IEA androgen metabolic process
GO:0008210 IEA estrogen metabolic process
GO:0008585 IEA female gonad development
GO:0009791 IEA post-embryonic development
GO:0014065 IDA phosphatidylinositol 3-kinase signaling
GO:0030165 IPI PDZ domain binding
GO:0031529 IDA ruffle organization
GO:0032587 IDA ruffle membrane
GO:0033327 IEA Leydig cell differentiation
GO:0035264 IEA multicellular organism growth
GO:0043325 IDA phosphatidylinositol-3,4-bisphosphate binding
GO:0045184 IDA establishment of protein localization
GO:0048008 IEA platelet-derived growth factor receptor signaling pathway
GO:0048705 IEA skeletal system morphogenesis
GO:0050853 IDA B cell receptor signaling pathway
GO:0051898 IMP negative regulation of protein kinase B signaling
GO:0060021 IEA palate development
GO:0060325 IEA face morphogenesis
GO:0070062 IDA extracellular vesicular exosome
GO:0070301 IDA cellular response to hydrogen peroxide

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000030064 plekha1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 protein_coding Danio_rerio
ENSDARG00000094504 PLEKHA1 (2 of 2) pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 protein_coding Danio_rerio
ENSMUSG00000040268 Plekha1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 protein_coding Mus_musculus

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