C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein phosphatase 3, catalytic subunit, beta isozyme
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000107758 PPP3CB 9606 - 10:73436428-73496024 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000342558 PPP3CB-002 73443780-73495996 protein_coding
  ENST00000360663 PPP3CB-001 73436428-73496001 protein_coding
  ENST00000394828 PPP3CB-201 73436806-73496024 protein_coding
  ENST00000394829 PPP3CB-202 73436806-73496024 protein_coding
  ENST00000430762 PPP3CB-003 73438198-73467619 protein_coding
  ENST00000495897 PPP3CB-004 73466958-73471577 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000342558ENST00000360663ENST00000394828ENST00000394829
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000342558 N/A 5.536±0.00 N/A N/A N/A N/A N/A 4.513±3.44 5.471±2.60 3.581±0.00 N/A 5.201±0.18 4.394±0.34 13.207±0.00
ENST00000360663 N/A N/A 2.297±0.00 11.132±0.00 N/A 4.654±0.00 1.649±0.00 N/A N/A 4.788±0.00 7.371±0.00 4.857±1.96 N/A N/A
ENST00000394828 9.815±0.00 6.951±0.00 2.627±0.00 N/A 9.017±3.37 18.535±13.12 6.202±0.00 0.659±0.00 9.209±0.00 N/A N/A 5.234±0.64 4.236±1.14 9.661±0.00
ENST00000394829 N/A 4.258±0.00 N/A 46.637±31.96 17.280±0.00 N/A 9.759±7.75 6.353±0.00 3.166±0.00 2.627±0.00 32.776±23.34 5.305±1.53 4.463±1.72 8.540±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000090 CIL_000090_0001 CGP 10:73423579-73496024
CIL_00008Z CIL_00008Z_0001 CGP 10:73436428-73625953

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001915 IEA negative regulation of T cell mediated cytotoxicity
GO:0004721 IEA phosphoprotein phosphatase activity
GO:0004722 NAS protein serine/threonine phosphatase activity
GO:0005509 IDA calcium ion binding
GO:0005515 IPI protein binding
GO:0005516 IDA calmodulin binding
GO:0005654 TAS nucleoplasm
GO:0005829 TAS cytosol
GO:0005886 ISS plasma membrane
GO:0005955 IDA calcineurin complex
GO:0006468 ISS protein phosphorylation
GO:0006470 ISS protein dephosphorylation
GO:0007165 NAS signal transduction
GO:0007507 IEA heart development
GO:0007612 TAS learning
GO:0007613 TAS memory
GO:0008144 IDA drug binding
GO:0010468 IEA regulation of gene expression
GO:0016311 IEA dephosphorylation
GO:0016787 IEA hydrolase activity
GO:0017156 ISS calcium ion-dependent exocytosis
GO:0019899 IDA enzyme binding
GO:0030018 IEA Z disc
GO:0030217 IEA T cell differentiation
GO:0030315 IEA T-tubule
GO:0030346 IDA protein phosphatase 2B binding
GO:0031987 IEA locomotion involved in locomotory behavior
GO:0033192 ISS calmodulin-dependent protein phosphatase activity
GO:0034097 IEA response to cytokine
GO:0035176 IEP social behavior
GO:0035690 IDA cellular response to drug
GO:0035774 ISS positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0042098 NAS T cell proliferation
GO:0042110 TAS T cell activation
GO:0043029 IEA T cell homeostasis
GO:0045087 TAS innate immune response
GO:0045893 NAS positive regulation of transcription, DNA-templated
GO:0046983 IPI protein dimerization activity
GO:0048167 TAS regulation of synaptic plasticity
GO:0048675 TAS axon extension
GO:0050796 ISS regulation of insulin secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000021816 Ppp3cb protein phosphatase 3, catalytic subunit, beta isoform protein_coding Mus_musculus

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