C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein phosphatase 3, catalytic subunit, beta isoform
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021816 Ppp3cb 10090 - 14:20499364-20546573 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000022355 Ppp3cb-004 20500030-20546512 protein_coding
  ENSMUST00000159027 Ppp3cb-001 20499364-20546573 protein_coding
  ENSMUST00000160812 Ppp3cb-007 20515448-20520721 retained_intron
  ENSMUST00000161332 Ppp3cb-005 20520608-20524043 retained_intron
  ENSMUST00000161445 Ppp3cb-003 20499868-20546547 protein_coding
  ENSMUST00000161989 Ppp3cb-002 20507671-20546440 protein_coding
  ENSMUST00000162107 Ppp3cb-006 20509449-20516016 retained_intron
  ENSMUST00000162217 Ppp3cb-008 20501552-20503770 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000022355ENSMUST00000159027ENSMUST00000161445ENSMUST00000161989ENSMUST00000162217
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000022355 4.332±1.27 2.205±0.32 6.688±1.32 8.847±0.87 3.938±1.29 1.873±0.78 2.219±0.50 2.462±0.51 2.392±0.73 3.907±0.99 9.311±0.11 2.511±0.75 3.024±1.02 0.972±0.07
ENSMUST00000159027 N/A 0.602±0.00 N/A 4.056±0.00 N/A N/A N/A N/A 0.891±0.00 N/A N/A N/A N/A N/A
ENSMUST00000161445 2.553±0.55 N/A 9.628±1.53 19.809±7.77 3.505±1.29 1.068±0.45 5.523±1.90 2.391±0.87 5.816±4.67 2.842±0.88 27.144±9.39 3.003±1.69 4.189±1.62 2.255±0.62
ENSMUST00000161989 3.694±1.31 2.956±0.00 5.416±0.30 11.770±1.23 5.799±1.87 N/A 3.262±0.51 5.628±0.00 11.027±5.23 5.819±0.00 N/A 7.108±1.74 5.494±2.46 1.594±1.09
ENSMUST00000162217 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.132±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000090 CIL_000090_0002 CGP 14:20482864-20546573
CIL_00008Z CIL_00008Z_0002 CGP 14:20499364-20618354

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001915 IMP negative regulation of T cell mediated cytotoxicity
GO:0004722 IDA protein serine/threonine phosphatase activity
GO:0004723 TAS calcium-dependent protein serine/threonine phosphatase activity
GO:0005509 ISS calcium ion binding
GO:0005515 IPI protein binding
GO:0005516 ISS calmodulin binding
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0005955 ISS calcineurin complex
GO:0006468 IMP protein phosphorylation
GO:0006470 IMP protein dephosphorylation
GO:0007507 IMP heart development
GO:0008144 ISS drug binding
GO:0010468 IMP regulation of gene expression
GO:0017156 IDA calcium ion-dependent exocytosis
GO:0019899 ISS enzyme binding
GO:0030018 IDA Z disc
GO:0030217 IMP T cell differentiation
GO:0030315 IDA T-tubule
GO:0030346 ISS protein phosphatase 2B binding
GO:0031987 IMP locomotion involved in locomotory behavior
GO:0033192 IMP calmodulin-dependent protein phosphatase activity
GO:0034097 IMP response to cytokine
GO:0035176 IEA social behavior
GO:0035690 ISS cellular response to drug
GO:0035774 IMP positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0043029 IMP T cell homeostasis
GO:0046983 IEA protein dimerization activity
GO:0050796 ISS regulation of insulin secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000107758 PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme protein_coding Homo_sapiens

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